Hmrz Posted April 10, 2014 Report Share Posted April 10, 2014 Has anyone had experience with this ds9 dx with this today after 3 days of what we thought were hives. Link to comment Share on other sites More sharing options...
MomWithOCDSon Posted April 10, 2014 Report Share Posted April 10, 2014 Vasculitis? My understanding that it is an auto-immune condition which results in inflammation of the blood vessels throughout the body. Yes, I have an acquaintance (a good friend of my good friend) whose son was diagnosed with this several years ago; apparently, he was in an extremely dangerous state at the time. This mom has since become very active in a foundation funding research, etc. and, so far as I can tell, is very knowledgeable about the condition. PM me if you'd like to get in touch with her, and I will do what I can to facilitate that. Sorry for this development . . . Link to comment Share on other sites More sharing options...
dut Posted April 10, 2014 Report Share Posted April 10, 2014 (edited) Just a thought but what meds is your son on? Our dd had a serum sickness reaction to penicillin which started with vasculitis. We also thought hives until we realized that they weren't coming and going as hives should but staying and coalescing/bruising etc. It might be worth googling serum sickness-like reaction. It can happen in response to other abx and I presume other meds too. Our dd's vasculitis went away fairly soon after stopping the abx but she continued to have other serum sickness symptoms for another 3 weeks or so. Mainly joint pain, at times severe. Edited April 10, 2014 by dut Link to comment Share on other sites More sharing options...
Hmrz Posted April 10, 2014 Author Report Share Posted April 10, 2014 Thank you for responding. Momwithocdson i will pm thank you. Dut ds was on augmentin for 7 months before switching to omnicef. After 7 days on omnicef the "hives" started. He is now off all antibiotics. I'm terrified about that but it seems necessary. He has been on steroids for the past 3 days and the rheumatologist decided to keep him on 20mg a day. Also he is 6 weeks post ivig. Poor kid they tried to take blood yesterday and he finally talked himself into after an hou only to have them put the needle in and get no blood. A meltdown followed and I can't imagine we will ever get him into that office or trust anyone enough to take blood again. What a mess. So happyto hear your dd recovered fairly quickly. I have read a little about serum sickness but I will dive deeper into it. Link to comment Share on other sites More sharing options...
PowPow Posted April 10, 2014 Report Share Posted April 10, 2014 One of my daughters developed hemolytic anemia post ivig. Vasculitis (or similar) developed. It was much sooner after ivig (like a week). It was monitored very closely by hem/onc and she was fine by 6 weeks or so later . She had type A blood, which apparently is more lively to develop this complication to ivig. Just something to consider. Link to comment Share on other sites More sharing options...
SSS Posted April 10, 2014 Report Share Posted April 10, 2014 I hate to say this, and certainly my perspective may be tainted, but when I first read this and saw vasculitis, I thought: Bartonella. Then you wrote it happened day 7 on Omnicef, maybe that is bringing it out? Here is a link saying Bartonella skin issues often misdiagnosed as vasculitis: https://sites.google.com/site/drjoneskids/tick-borne-diseases/ba Just wanted to mention the possibility... Link to comment Share on other sites More sharing options...
dut Posted April 10, 2014 Report Share Posted April 10, 2014 7/8 days is the classic timeframe for serum sickness-like reactions to happen in response to meds. It is a Type III delayed hyper sensitivity. I would have a good look at that as a possible. If that is what he is dealing with, it should take 3 weeks for symptoms to resolve as that's the half-life of the antibodies produced. The vasculitis and other issues are caused by the deposition of immune complexes in organs ie skin and joints. My dd had vasculitis that did go fairly quickly, about 2-3 days after stopping the abx, (that was replaced by dermagraphism), body swelling that also went when we stopped abx. She had horribly swollen, bright red and hot knees and elbows, followed by severe at times joint pain. When the pain was severe, she couldn't walk. We were told to use benadryl at full dose, double dose zyrtek and full dose ibuprofen. This kept her comfortable most of the time. She was evaluated for rheumatic fever due to the joint involvement swelling etc but came back negative and magically at the 3 week mark the pain subsided and resolved over a couple of days. My daughter can happily take azithromycin but as penicillin was her trigger can no longer take those. We also avoid cepholasporins (sp?) as they can cross react with penicillin allergies. So even if it is serum sickness it shouldn't mean he has to avoid all abx. Good luck... Link to comment Share on other sites More sharing options...
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