Cam Kinase & Viruses

[trintiybella]

Can the Cam Kinase be high because of viruses?

[norcalmom]

Did you have your child's Cam K II tested?

 

It is a measure of an autoimmune reaction, not directly of infection, but it is raised during after and infection, and can continue to go up and stay raised after a known infection - an indication that the body's immune system has gone awry and it now attacking itself.

 

I do know if can be slightly raised due to a bacterial infection ( strep) in NORMAL, non-pandas blood - but it does not go very high, and returns to normal after the infection resolves. PANDAS subjects, go very high and don't return to normal, even after the infection is cleared. I do not know if other infections have been tested in the normal population so that comparisons can be made. Cunningham has data, and I hope to see her publish these finding in the near future now that her lab is open. I would think she would be publishing some papers to support her lab's commercial endeavors and convince doctors that her tests are worthwhile. The inital papers had very small subject groups, and that was a big criticism for her tests. But she now has many year of data that can be published.

 

My personal favorite theory on this is that reccurrant infections, of various types (some identified, some yet to be identified) and probably other factors, break down the tight junctions Blood Brain Barrier, similar to what happens 24 hourse after a stroke, allowing the immune system access to neuronal tissue and keep telling the body to make more and more of the auto-antibodies that are found in pandas blood. There is also the possibility that the key autoimmune reaction is that self is attacking the BBB, and flairs allow permeability in the BBB and thereby access to neuronal tissue. Similar to what is postulated in MS. That it is a disease of the BBB, not the brain per se.