Elevated B12

[SurfMom]

Researching tonight on B12. In DD15, the only test that came back out of range on the the night of her first exacerbation was B!2. Now I am going back and looking at possible peripheral neuropathy.

 

Anyone else with high on this screening?

[colleendonny]

My daughter had almost double the normal B12. Dr. B isn't concerned, nor is her LLMD. Still worries me somewhat.

[LNN]

You may want to test for an MTHFR mutation. One possible reason for high B12 is that you could have a folate block. If your body isn't converting folate into methylfolate, then you don't have enough methylfolate hooking up with B12 and using that B12 to fuel the methylation cycle properly. So you think "high B12 - that's good" but maybe it's not. It could be a sign of a log jam.

 

I know methylation makes a lot of people get that glazed look in their eyes. It's a complicated topic. But Sheila Roger's next Latitudes publication will include a long article on the subject. You may want to PM her and ask about a subscription (very affordable). You can find her contact info by clicking on her name on one of the threads she's posted at the top of the Pandas forum main page.

[sf_mom]

In addition to checking for methylation issues you might also check for heavy metals at the same time. A good LLMD, integrative Dr. or DAN can help with testing and treating.

 

I've attached an interesting article on Copper Toxicity but it also discusses heavy metals, vitamins, KPU and the intricate balance between these elements/vitamins and detoxification.

 

http://www.tvernonlac.com/copper-toxicity.html

[SurfMom]

Thank you both. I am all over the methylation cycle, learning about it to the nth degree to be able to present my concerns to her doctors cogently. Both of you have me sensing I am on the right track. Thanks to for the heads up on the heavy metals. On that next.

 

Great timing with Sheila Roger's pub.

 

It is interesting how many elevated, though slight, results in DD's blood panel that were dismissed during her first dx. Everyone is more than willing to treat the symptoms but digging deep for the root of the cause is falling squarely on me - as has been the case for so many of you.