Does inflammation cause any permenant damage

[LaurenK]

Does this constant inflammatory state with PANDAS cause any long term damage?

[beeskneesmommy]

That's the million dollar question. However, I can say that my son has had some pretty severe "brain fog" among other typical PANDAS symptoms, repeatedly over the last several years. When he comes out of flare his thinking and functioning is just fine, even a little advanced for his age. It is clear that he is still able to learn an develop in part, even when he is doing poorly. It is important to catch it ASAP when you see them start to show signs of a flare. We use Ibuprofen and when the flare is longer lasting, we have used steroids which generally give us great success. If this pattern has continued for a long period of time as my son's has, and you have exhausted other treatments (DS5 has been on Augmentin and Azith daily for a year and other abx for a year prior), it may be time to take a look at the IVig as an option. In addition, it is important to note that the abx combo has taken my son very far. He is much better. However, all symptoms have not subsided which is why we are working toward precert for IVig at this time.

[MomWithOCDSon]

I don't know if you're referring to "brain damage" specifically, but in terms of whether or not persistent inflammation can do "damage" to a body and its organs, I think the scientific response is overwhelmingly "yes."

 

I heard an interesting story on NPR the other day, discussing the fact that now, thanks to advancements in antiviral drugs especially, thousands of people have been living with HIV infection for decades, keeping it at bay with the antivirals. What the doctors note, however, is that the almost constant state of inflammation engendered by the autoimmune response to the virus living within and/or the daily drugs takes an additional toll on internal organs as compared to "healthy controls." So people living with HIV, even though the virus can be lying "dormant" at undetectable levels at points in time, have increased rates of heart, liver, kidney and muscular-skeletal ailments earlier in life.

 

Inflammation is Enemy No. 1.

[laure]

I don't know if you're referring to "brain damage" specifically, but in terms of whether or not persistent inflammation can do "damage" to a body and its organs, I think the scientific response is overwhelmingly "yes."

 

I heard an interesting story on NPR the other day, discussing the fact that now, thanks to advancements in antiviral drugs especially, thousands of people have been living with HIV infection for decades, keeping it at bay with the antivirals. What the doctors note, however, is that the almost constant state of inflammation engendered by the autoimmune response to the virus living within and/or the daily drugs takes an additional toll on internal organs as compared to "healthy controls." So people living with HIV, even though the virus can be lying "dormant" at undetectable levels at points in time, have increased rates of heart, liver, kidney and muscular-skeletal ailments earlier in life.

 

Inflammation is Enemy No. 1.

 

Bumping