levofloxacin

[melanie]

Does any one use this for mycroplasm or PANDAS?

[laurenjohnsonsmom]

Levofloxacin for the treatment of Mycoplasma pneumoniae-associated meningoencephalitis in childhood

Susanna Esposito, Claudia Tagliabue, Samantha Bosis, Nicola Principi

Department of Maternal and Pediatric Sciences, Università degli Studi di Milano, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122 Milan, Italy

 

Received 13 December 2010; accepted 12 January 2011. published online 07 March 2011.

 

Abstract Full Text PDF References

Abstract 

It has long been postulated that Mycoplasma pneumoniae plays a causative role in the development of neurological syndromes and this has recently been confirmed by highly sensitive and specific molecular diagnostic techniques for identifying infection due to this pathogen. Encephalitis and meningoencephalitis are the most frequent M. pneumoniae-associated neurological manifestations. Macrolides are considered the antibiotics of choice for treatment of paediatric M. pneumoniae infection, but the increase in macrolide minimal inhibitory concentrations of a substantial percentage of M. pneumoniae strains and the poor penetration of macrolides into cerebrospinal fluid suggest that drugs other than macrolides should be evaluated. Here we describe five paediatric cases of M. pneumoniae-associated meningoencephalitis in which 14 days of intravenous (i.v.) administration of levofloxacin (25mg/kg/day in two divided doses) led to the disappearance of neurological signs and symptoms, wi!

th a good safety profile. Although further studies are needed to demonstrate whether or not M. pneumoniae-associated meningoencephalitis should always be treated with antimicrobials, what the drug of choice is, how long therapy should be administered and whether supportive therapy is useful, these findings suggest that i.v. levofloxacin should be considered for the treatment of paediatric M. pneumoniae-associated meningoencephalitis.

 

I have copied this abstract for us in my ongoing quest to figure out chronic high mycop IGG numbers for my dd over the course of more than 2 years.  Biaxin and minocycline did not show sustainable gains after multiple high-dose courses over said time.  

[JAG10]

I'm confused. Lots of chat about high myco-p IgG, which I understand is a concern.....but if your child is getting IVIG, the myco-p IgG is going to go up, right? I thought if a child receives IVIG, we should only be monitoring myco-p IgM?

My dd myco-p IgG was tested Before and after her first IVIG. It doubled to 3.1. My impression was they don't even look at the IgG anymore because they know it is inflated from the donor antibodies, so it doesn't give them any meaningful info. Maybe I misunderstood?

[melanie]

I lost 2 posts

 

Any way going to the neurologist tomorrow Im going to request the test to detirmine wether or not danny has this Which specific test will detirmine this as a fact! DONE with speculations DONE!!

[coco]

Melanie, scroll down a bit to the original chronic mycoplasmas IGG Post, there you will find my complete post and link to full research article you can read, print and take to your doctor. Hope it helps. Pm me if you can't print it out for some reason.