MY ASO elevated? What?

[beeskneesmommy]

OK, so I had a routine physical a couple of weeks ago and just for the heck of it, threw in my ASO and Anti-DNase. The ASO came back elevated, which would indicate recent Strep infection. I had several "colds" in a row about 6-8 weeks apart, all very familiar, and mostly the same - slightly irritated throat turning to a stuffed up nose and them leaving the system fully after about 5 days. I have been getting these things since my son was born 5 years ago. In the same token, my son has had a really rough time w/PANDAS flares for the past couple of months. Things that make ya go "Hmmmm". Strangely, the Anti-DNase was within normal range...what do you all make of that??

[JAG10]

When we first consulted with Dr B, Nov 2010, he ran certain bloodwork on the whole family including ASO and anti-DNAse B.

Neither dh nor I had been sick in recent memory. Both of us had elevated ASO, but not DNAse B. Both girls had elevated ASO and higher DNAse B and acted like it. I think they brought strep in the house and we reacted to it on a cellular level, but never got ill.

I don't know where I got this impression, but I've had it for 2 years now....that elevated anti-DNAse B is more indicative of pandas/pans than elevated ASO. Obviously some have no titer rise and that doesn't exclude pandas, but my girls' symptoms have always correlated to the height of the DNAse B titer. In fact, dd12 recently had a strep infection (asymptomatic) where the ASO was higher than the DNAse B and her behavioral symptoms were so mild I wasn't even sure it was anything until we had the blood tests, so that's interesting to me. I'd bet you if it had been the other way around, I would have had no doubt what was going on!!!!

[beeskneesmommy]

My son usually has both ASO @ Anti-DNASE elevated when he has a flare, but I am not sure why I have higher ASO. Prior to having his T&A 8/2010, I got Strep x 2 from him although I had not had it in 30 years that I knew of, since I had my T&A at age 17. Rapid came up + w/no tonsils and my doc was amazed. My son reacts to people who have Strep around him, although he shows no signs of infection other than elevated titers (and PANDAS symptoms). I think he may have had his 1st Strep infection at 14 WEEKS. It was afterward that I started to get sick w/ this familiar respiratory "cold" that sometimes would last and last, producing a dry cough that went on and on sometimes for weeks, and a loss of voice. I am thinking that I may be a carrier and he is reacting to me?? How do you actually identify a carrier?

[fightingmom]

I need to get on the ball with this titer stuff. It's the one thing I really can't wrap my head around. My son did not show any ASO, but has DNase of 273 (off the top of my head, maybe I'm off a little). Does that indicate he does or recently did have strep? Sure would account for his behaviors the past few months!