michelew Posted March 27, 2012 Report Posted March 27, 2012 My son has been on Doxycycline (200mg/day)for almost 6 mos. After two months of being on Doxy, we added Azithromycin (500mg/daily). He did well on this combo for a short while, but then started to backslide & his IGM numbers weren't really changing. As a result, we swapped out the Azithromycin for Biaxin about 3 weeks ago, and now his IGM numbers are beginning to fall again. Clinically, we haven't seen much improvement, but we were happy to see that his IGM number went down more than 500 points in less than two weeks, after switching to Biaxin. I'm now wondering if we should add Flagyl into the mix, as I have heard that this kills the cyst form of Mycoplasma. I think that I have seen on this forum that some of the kids being treated for Myco actually use something called Tindamax. Is this the same type of abx as Flagyl? Also, I think I recall seeing that it is often pulsed on weekends, as opposed to taking it daily. If you are being treated for Myco, and are on combo abx, I would be interested in hearing what combos you're on & also what dosing. I am particularly interested in hearing from those of you who are taking Tindamax and/or Flayl, and the what dosing schedule you are following. Thanks!
LNN Posted March 27, 2012 Report Posted March 27, 2012 You may want to post this on the lyme forum, where tindamax and flagyl are more commonly used (they are similar - I see tindamax used more for kids). My DS took tindamax on weekends (4 doses fri pm - Sun am) and then 5 days off. It kicked his butt big time. We had severe herxing and eventually had to stop. However, we enjoyed a long stretch of goodness once things calmed down after that. To do it over again, I'd have done only 2 doses on Fri pm/Sat morning for a few weeks. Then if herxing not horrible, I'd have gone up to 4 doses. The way we did it produced such an inflammatory response that backing down half way didn't help. The inflammation was already there. We may have been able to stay on it longer if we'd started slow. Make sure you have a good detox plan in place before starting. More than half of the response is due to die-off toxins and the body's inability to clear junk out of the way quickly. Steady dosing of iburpofen helped as well.
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