More CAMKII

[MomWithOCDSon]

Full disclosure: we never had the Cunningham CamKII test done for our DS, so we haven't had the full benefit of not only the test, but the test results explaining the whole thing. I've read through Buster's explanatory posts and some of the other "history" on the topic, though.

 

Am I correct in understanding that it is a high CamKII measure that is thought to be indicative of PANS?

 

If so, then what do you "sciency" types make of this new paper? Maybe it's that you want neither too high nor too low CamKII measures?

 

CamKII and Neurotoxicity

 

[911RN]

Full disclosure: we never had the Cunningham CamKII test done for our DS, so we haven't had the full benefit of not only the test, but the test results explaining the whole thing. I've read through Buster's explanatory posts and some of the other "history" on the topic, though.

 

Am I correct in understanding that it is a high CamKII measure that is thought to be indicative of PANS?

 

If so, then what do you "sciency" types make of this new paper? Maybe it's that you want neither too high nor too low CamKII measures?

 

CamKII and Neurotoxicity

 

 

Just like Goldilocks and the Three bears. This one was too hot, this one was too cold, this one was just right! This one was too hard, this one was too soft and this one was just right. Geez, I need to go to bed!

 

I have read Dr Cunningham's papers ad nauseum and yes, you are right- high Cam Kinase II is indicative of PANS, super duper high can mean SC. Not sure what to think of the paper. Too low- neurotoxicity. Too high- psycho/motor toxicity?? Not sure I can tell the difference. But it did have a sentence or two on glutamate for you to sink your teeth into, Nancy:)

 

In full disclosure- our testing was never completed- program shut down although specimen was sent to lab in OK.