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huntington's disease/yeast/kynurenine !


Guest daniel quan

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Guest daniel quan

from

http://www.nature.com/ng/journal/v37/n5/ab...abs/ng1542.html

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Among the most potent suppressors was Bna4 (kynurenine 3-monooxygenase), an enzyme in the kynurenine pathway of tryptophan degradation that has been linked directly to the pathophysiology of Huntington disease in humans by a mechanism that may involve reactive oxygen species4. This finding is suggestive of a conserved mechanism of polyglutamine toxicity from yeast to humans and identifies new candidate therapeutic targets for the treatment of Huntington disease.

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And kynurenine is suppressed by Magnesium which many people here found success with yeast being eliminated.

 

So with Yeast removial and Magnesium therapy ...kids should do lot better ...

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