Immunoglobulin A ?

[Joan Pandas Mom]

My son's Immunoglobulin A Qn, test came back 92 with reference range 61-348

IgA, Subclass 1 57.3 LOW range being 58.2-263.5

IgA, Subclass 2 7.6 LOW range being 12.2-140.7

What does this mean?

[norcalmom]

I dunno. google it. might mean that if you do ivig you are at risk for anaphylactic shock. but, I think they have immunoglobulin with out the IgA for those patients. Below is taken from a site talking about it...but they are tlaking about patients with NO or REALLY low IgA. Your child has some, even in the normal range over all.

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"Patients with IgA Deficiency are often considered to be at increased risk of anaphylactic reactions when they receive blood products (including IVIG) that contain some IgA. This is thought to be due to IgG (or possibly IgE) anti-IgA antibodies which may be found in some of these people. However, it has been observed that many patients with IgA deficiency do not have adverse reactions to blood products or IVIG. There is no agreement among experts in this field regarding the magnitude of the risk of these types of reactions in IgA deficiency, or the need for caution or measurement of anti-IgA antibodies before administration of blood or IVIG to these individuals.

[Joan Pandas Mom]

I just asked Dr.'s office. They need the results to determine what type of Gaummeguard they give. It doesn't have anything to do with his immunity, what I was thinking. Thanks though.