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Sorry- misspelled the title!!! I have spent the last several days reading the "internet" regarding MTHFR and nutritional balancing. It's taking me a bit of time to digest. I know there are some very knowledgable people on this board - LLM in particular i know has extensive knowledge in this area. Would love advice as to where to start? 23&me as first step? Here are a few "abnormalities" : Complains of joint pain, fatigue, facial flushing.. and episodic anxiety OCD, depression et cetera et cetera-- PANDAS/PANS since age 7 (maybe 5). Labs below drawn after "sporadic" occasional multivit supplement that did have alot of B12 500 mcg and 400 mcg folic acid: (but we gave him this only 2 -3 times a week for just a few weeks prior to labs). B12 HIGH (1467) (reference range 211-946) FOLATE Upper levels >19.9 (reference >3 is normal) Ferritin alwasy runs at very bottom or reference range. Chronically swollen nasal turbinates/ sinus infections. TSH was consistently high despite normal T3-T4. Placed on levothryoxine all values have remained stable on medication X 2 years. Anti- adrenal antibody confirmed presence. Normal is less than 1:10. DS level was 1:10. No one seems to think this is a problem including our endocrinologist. Ig E low 2011 bu high (just outside reference range) with last test November 2013. Mild G2 and G3 subclass deficiencies. My question: our psych doc recommends inositol. I don't want to add anything else until I understand more about his MTHFR status. Any clues above? Do we order and wait for 23&me kit despite it's more regulated limitations?
