Anyone else with kids who are generally immune deficit? DS18 has been on prophylactic bactrim during 1st year in college (after having tonsils out last spring). We had anticipated weaning him down and then possibly off by next fall. But now his labs are showing IGA and IGM deficiencies. Still has a CVID, as well, but not low enough to qualify for IVIG. I had thought DS would eventually be entirely off of antibiotics, by the end of his time at university, at the very latest. Now it is looking like he may be on them indefinitely. Are others in this boat? If so, how are you coming to terms with the possibility of daily antibiotics for life?