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I found an article by St. Jude Children's Research Hospital that talks about this gene and there is an enyzme test that also checks for drug response. This gene showed up on my son's Detox Profile. However, I am confused because this article does not mention the varations of this gene but I am wondering if this is the reason why my son does not respond to pain medications. The gene CYP2D6 S486T showed +/+, CYP2D6 100>T +/- and CYP2D6 2850C>T was +/- on my son's Detox Profile. Could this mean that my son might have a problem with metabolizing certain medications? I have sent this information to my son's doctor but was wondering if anyone else was dealing with this possible problem. http://www.stjude.org/stjude/v/index.jsp?vgnextoid=4d00b53d06550310VgnVCM1000001e0215acRCRD
