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  1. So I got my husband's 23andme results and plugged it into genetic genie. My head is spinning. Just as a background, he was likely PANDAS as a child, has likely vaccine injury from the gulf war (13 or so vaccines before deployment) and recent rheumatic fever w/ regression into adult PANDAS like symptoms. He's in a much better place now, after long-term antibiotics. his results-- MTHFR Homozygous (+/+) C677T mutation Other mutations-- Homozygous (+/+) mutations: · COMT V158M · COMT H62H · MAO-A R297R · BHMT-02 · BHMT-04 · BHMT-08 · CBS A360A Heterozygous (+/-) mutations: · VDR Bsm · VDR Taq · MTR A2756G · MTRR K350A · AHCY-01 · AHCY-02 · AHCY-19 · SHMT1 C1420T I honestly don't know where to begin. He pretty much has defects throughout his methylation pathway. I gather from my brief reading that he won't tolerate methyl donors well, so hydroxy B12 better? Is methylfolate still ok? I know he needs folate b/c he has high homocysteine levels. No need for anyone to reply I'm just thinking/planning out loud.
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