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Received CBD oil and started with 15 drops twice per day, today. DD has needed melatonin for sleep for a few years, but I can't find information about the interaction of the two. Found some information that CBD oil may help her sleep, but not sure if I can't also give melatonin. Won't give melatonin tonight. Hope she sleeps... Anyone know about this?
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I'm wondering if anyone here has had cytochrome P450 testing and how the results helped you/your child. As I've been reading about CBD oil, checking for potential problems, I've read that it uses these particular enzymes from or in the liver (CYP450 or P450). Seems there could be drug interactions with other drugs or supplements that use these same enzymes. The effectiveness of the drugs/supplements could be altered. When I check for general drug interactions and look at the professional information, I also see mention of CYP450--for many of the meds my DD is taking or has taken. Then I remembered an article I read and saved when we sat in the Mayo Clinic for CBT a year ago. I pulled it out and sure enough... A man was found to be a poor metabolizer of medications so they built up and became toxic. This was found by testing his CYP450. His history was 16 years of struggle with OCD, depression, anxiety, fatigue, tremors, abnormal thyroid function...all following a simple strep infection. When I read more about CYP450 testing, it seems it is used when people respond poorly to SSRIs. Hmmm. DD has been on 3 different ones now. Any thoughts on this?
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- liver enzymes
- drug toxicity
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