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I've read some old threads on IGeneX Lyme Western Blot, so I know that only some bands are specific for Lyme. However in viewing DS's results, I was surprised that IGeneX does not count any indeterminate bands, though many LLMDs seem to. What's the reason for / against? Can someone help explain whether DS does or does not have Lyme and/or babesiosis? Borrreliosis Western Blot bands: (I mark in RED the bands IGeneX states are specific for Lyme) 18 23-25 28 30 31 34 39 41 45 58 66 83-93 IgM - - - - I - - I - + - I IgG - - - - - - - + - - + - Babesiosis: B. microti IFA - IgM Serum 40 (neg < 20) B. microti IFA - IgG Serum < 40 (neg < 40) Babesia FISH Whole blood Neg BTW: He had been on Zithro for months, but was off Zithro ~ 6 days @ blood draw). So, can some of you veterans help me? What does the Western blot mean regarding a Lyme infection? How long do the IgM levels stay elevated? Should I think of him as having Lyme or not? How likely that he would have a co-infection w/o the Lyme itself? If IgM B. Microti is positive, wouldn't he also be positive by FISH? Are LLMDs pretty consistent in how they'd interpret this, or does it depend on the MD? Thanks. wisdom-seeker PS. DS had his first IVIG a month ago, and I need to decide when to repeat. He seems a bit better, though his headache is constant and annoying. And this week his anxiety and intrusive thoughts are off the chart, and he's feeling very off. Still, I don't want to repeat IVIG if we need to treat this stuff first.