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Dd has been making great strides over the past few months, increasing and steady progress, with 2 minor flares associated with colds (sneezing, coughing) that cleared up rather quickly. The past couple of weeks, her anxiety seems to be up, in an "on and off" fashion, and she has been having brief but intense moments of aggressive/ODD behaviors. For instance, yesterday I was brushing her hair, and it was "hurting" her head, so she got very angry, stomping around, smacking me, etc. -- not full blown raging, just a few minutes of nasty, unreasonable behavior..... This morning, it was her brother interrupting her with a video game she was trying to help him with. She got unreasonably angry, hitting me, saying she hates both of us, etc. For the last month, this has been happening every once in awhile, but it seems like the past week or so it's been happening more frequently. The few months prior to that she really hadn't had any behaviors at all and was making progress with other symptoms too (eating, etc). We just got Spectracell results and some others.... The biggest, glaring result was her antioxidant function which was very low-- her glutathione level was completely tanked-- her Pans doctor said he's only had 2 patients with levels that low ever, and he is the only doc in this area that even does Spectracell from what I understand. So, we started S-Acetyl Glutathione last Monday, it's been 6 days. Question- could this be causing any sort of herx or issues? She's been having more "micro" odd/aggressive episodes in the past week than she has in months. Her doctor said we shouldn't see any issues because of the Acetyl glutathione, so I don't know if she was just heading in this direction anyway, or if it's causing a problem? Other results- positive for one copy of c677T mutation MTHFR (negative for A1298C) C4A level high at 6113, mycoplasma pneumonia IGM finally in range at 639, but IGG still >5. Total antioxidant function- deficient. Thoughts and suggestions appreciated! Lately when she has behaviors, all I can think to myself is that I'm SO SICK OF THIS she was doing so well, and she's still so much better than she was, but it's hard to see her having issues frequently again after such great progress. Hopefully just a minor setback.