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I feel like the Needy Forum MOM !! I write on here often lately because it tends to give me some relief! Thanks you !!! Your advise is always helpful!! Our Ds tends to be sad and depressed often with frequent crying bouts . He was never moody or sad in his life until now. Is this PANS?? Or is it Bart? Can this be Pans Flares in him? or does Lymes have to be in the picture for such strong neuro reactions??? He was treated for Bart for past 6 months and at first he was great no more rages and more improvement's but then after several month. he began to decline and now sad and cries often . Like before treatment. SSRI's only cause him psychoses. WE also started treating Babasia but the Malarone makes him more depressed so that we had to stop after 10 days. We have two top doctors but they disagree as to whether he has Lymes at all bc Igenx came back negative. One wants him full force on Babs treatment and the other says no. Hmmmm confusing I know! We decided to treat on clinical anyway but his sadness and crying has flared again and it's awful to watch. I am waiting on more lab work and he currently is only on zith 1 x aday. Other anti b's were causing side effects so we removed all for now. He began throwing up with Augmentin and could not walk well on the Omnicef. AND Bactrim made him so dizzy !! He did well on these meds for several months but eventually all began to negatively effect him. I am testing my home for mold as we write. I give high doses of quality probiotics. I even stopped supplement's to see if his body just needed a break. Appt with Dr T Friday to read lab work and hoping some virus is the culprit. Does anybody have PANS child who has this emotional labiality?? He doesn't get anxious much and his OCD is not very typical OCD. He is also on low liquid lithium and has been for 6 months. (very low)1/4 ts a day. I really hope the new lab work shows some answers. NO school and rarely wants to leave the house. Much blessings to all!!