zma13

I have two boys with Pandas. They have both had some of the tics that your son has. My youngest still smells his finger. Somedays more than others. He alo had a nose sniffing problem, he did not need to blow his nose but would continue to sniff. These tics seem to change but never go away. Everyone didn't notice my sons tics at first, but I did. There are times that I sit and watch to see what tics are still there.

and If you can relate any of this to the strep/PANDAS studies, maybe it would provide some clues. I don't know if there is anything helpful here or not? If you stare at these words longs enough they start to make sense, honest ^ http://www.ncbi.nlm.nih.gov/pubmed/18219588? ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA&linkpos=1 Histidine-Rich Glycoprotein Modulation of Immune/Autoimmune, Vascular, and Coagulation Systems http://www.nature.com/icb/journal/v83/n2/abs/icb200514a.html immune complex clearance and phagocytosis of apoptotic cells. http://www.ihop-net.org/UniPub/iHOP/pm/104...p;pmid=15225155 Apolipoprotein H (APOH), also known as beta2-glycoprotein I, is a major autoantigen for the production of antiphospholipid antibodies (APA) in autoimmune diseases. APA is also recognized by a cryptic epitope generated following the interaction of APOH with anionic phospholipids (PL). Thank You

Right now this is no plan for the boys. The youngest one was on amoxicillin for a year and he had is tonsils removed a year ago. These two things did help with the strep. They did this only for the youngest. His titer was extremely high and he continued to get strep. The doctor thought it best to put him on the antibiotics to keep him form possibly getting rhem. fever. He never showed any signs of being sick. No sore throat, no fever, he didn't even feel sick. He just started on morning with tics, I took him to the doctor and thats when he had the high titer. Both boys now get tics when they are sick with anything. They don't need strep for the severe tics to start. I know that they can have different forms of tics at different times. I have to watch for the tics or behaviors to change so I now if the boys are sick. Before the tics started both boys would run extremely high fevers for the slightest reason. They both had strep infections before with fevers. Once the tics started my boys do not run fevers for anything. I just have to watch for problems. Antibiotics do help the tics when they are severe, doctors can't really tell me why they seem to help. The boys tics never competely go away, they can't tell why on this either. Because the boys do not run fevers or get sick with the strep, I asked the doctors if this was caused by a strain of strep, all they could say is research is still being done. I just came across this sight in the last couple of days. Five years ago when this all started they was very little I could find. A doctor in the same ped. practice I take my boys to, told a friend of mine that strep did not do this to children. I wonder in five years if she has changed her mind. My sons have been tested for about everything because I did not believe this could happen from strep. There was very little literature I could find, and nobody had heard of it. On my mothers side of the family, my aunt, grandmother, and great-grandmother had rhem. fever. I have watched family members at any of our family reunions I attend for signs of tics, I have not seen any, no one knows of any either. My question now that can't be answered is will they outgrow it, will it become worse with age.

I have two sons who have been diagnosed with P.A.N.D.A.S.. I can tell you that each one has had different sorts of tics and behavior issues. I have been dealing with this for 5 years. They both started at age 10 with the severe tics. Looking back I believe the problem started earlier, but the severe tics brought everything to light. Neither of my sons have the piano fingering you mentioned. You stated that you son was checked for strep, was this a throat swab or in blood work. I ask because when the tics started in my middle son he had been seen at the doctor because he felt like he had strep, they ran the rapid throat swab test and it was negative. Two weeks later when the tics started, they checked his blood and found evidence of a strep infection. I was told that he probably had a strep throat that went undiagnosed because the rapid test didn't pick it up.