Your advice is needed and any guidance would be greatly appreciated. DD6 started showing OCD signs in December. She can still function but is not the same happy child she was just months ago. Constant worry and irrational negative thoughts are taking her over. When researching it, I came across PANDAS. All of the information seemed to fit our situation. DD was sick with a fever the first week of December. Didn't show other signs of strep so when fever finally broke and she got better I didn't think anything of it. A week later, she couldn't stop obsessing over being wet with urine, having clean hands, thinking that she was doing harmful things, etc. Had to wait until 1/9 to see pediatrician about onset of OCD. Luckily the pediatrician was open when I suggested PANDAS. Rapid strep test was negative (although I don't think they got a very good swab). ASO was positive with a titer of 400. AntiDNase-B was 140. Doctor said this ruled out PANDAS. She had prescribed antibiotics and instructed us to go ahead and continue treatment. DD is taking Cephexalin 250 mg 3 times a day. We are on day 8 and there really hasn't been a change in behavior. We have a follow-up appt. in about a week. I guess I'm not sure where to go from here? Do our test results rule out PANDAS? Should I ask for DD to continue on longer course of antibiotics? Stronger dose? We are just starting out on this journey and I hope all of you who are more experienced can help out these worried and confused parents.