My wife has autoimmune deficiencies, and I feel this has either caused or contributed to a LOT of the health problems she has had. I've never met or heard of anyone who has as many "issues' as she does, from hypoglycemia, to Sjogren's, to Rheumatoid Arthritis, to kidney stones, to Endometriosis, to migraines..., etc. Our DS [now 8 y.o.]was diagnosed with PANDAS in June of 2011, and has autoimmune defic. Now, that our DS was diagnosed with PANDAS, it's obvious our 28 y.o. DD has had it since she was 11 y.o.