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A little bit about ASO Titers


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HI

The thing that doesn't make sense is that by going off anti-biotics, the PANDAS symptoms get worse. Why? It has

to be the titers that are causing this, no? Thanks

 

During the worst of my daughter's illness her titers where ASO 6 and Anti-Dnase 95. Both very low. Yet, 6 weeks of abx and she was almost back to 100% herself.

 

Anti-biotics have an anti-inflamatory property is how most seem to believe they help:

 

"Although the empirical use of some antibacterial agents in various inflammatory diseases has proved beneficial in the past, it is only recently that the therapeutic anti-inflammatory potential of cyclines and macrolides has received attention worldwide. "

 

 

NCBI article

Edited by Mayzoo
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HI

The thing that doesn't make sense is that by going off anti-biotics, the PANDAS symptoms get worse. Why? It has

to be the titers that are causing this, no? Thanks

 

Well, not the ASO and AntiDnase titers- but other antibodies to strep (or some other infection). Also, some abx have properties other than being antimicrobial- anything anti-inflammatory would help and some have immune modulating properties and it seems like I remember that some abx even increases serotonin.

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