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Please help! Please help! Aggrassive behavior/worse sleeping/possible illusion


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Dear all,

My DS 15 has Bart purple rashes on his body for since last year. He started Biaxin (replaced Azithromycin) nine weeks ago. 500 mg twice a day (continue with Rifampin). Since he had more aggressive and uncontrolled behavior, it was reduced to one Tab in the morning weeks alter as the recommendation from our LLND. His outburst was reduced, less OCD but took longer time to fall asleep.

Starting from three weeks ago, he again had outburst 1-2 times per week. He hit the wall, counter, door and even hit me and his grandma uncontrollably. He shook his arms (new symptom), took his shirt off and dumped on the floor, threw his glasses, jumped, screamed and ran. He seems think about things in opposite way. (For example, he complained the food is cold when it is very hot. He said he is happy when he looks sad, or said he is sad when he actually is not). He may have an outburst suddenly with yelling.

His repeating talking came back. He insisted to ask to “I want to go the shopping mall / piano lesson NOW” at bed time over and over although I responded him “tomorrow and Tuesday” multiple times.

Two days ago, he even said he wants to put his glasses to the toilet and flush it. He took his watch off and dumped it somewhere, but he couldn’t remember. He also complained that his stomach “hurt” frequently. He had little watery stool for a few days until yesterday. His underwear again always has little watery stool (He did have this symptom before starting the treatment and got better when taking Rifampin combo with Azithromycin. It came back this time)

His sleeping became obvious worse. I asked him to go to bed 10:00 –10:30 pm but he got up from the bed and walked to me asking “please take my watch off (on)/ I want to drink water (although I told him the water bottle in his bedroom and he knew) over and over. He cannot fall asleep until middle of the night and wake up at 5:00 to 6:00 am.

Not sure if Biaxin did something negatively to him. But Rifampin (on 600mg) has been very helpful for him.

1. He seemed frozen for 10 seconds during piano playing or speech therapy and no response when I called him. Is it kind of seizure symptom?

2. He seemed better when was taking Rifampin combo with Azithromycin  but LLND mentioned that antibiotics need to be changed every three months.

My DH asked me to STOP all antibiotics immediately because he thinks these “drugs” caused his son “having illusion”. He said “He is now turning from a autistic patient into a mental patient. I suspect he is now having imaginations in his mind which trigger his recent behavior. This kind of behavior is showing him to have mental problem…” He concerned if my DS will have more aggressive behaviors when he grow up.  

I knew it is because of the infection and it needs to take time to be treated. But I don’t know how to persuade my stubborn husband that the boy needs to continue the treatment.

3. Can anyone share what will happen if take all antibiotics off when the infection is still there?

I’m very miserable and feel hopeless.

Any advices/sharing will be appreciated!

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