need help understanding WBC and abx protocol

[BeeRae22]

So, dd's WBC just fell again. Last winter/spring is was borderline low at 4.1-4.3 most of the time. When she saw the greatest recovery/progress, WBC went into range at around 6. Now, early January she dipped down to 4.1 again. Just got retest results and shes down to a concerning 3.0

 

We are having another CBC drawn to see where she is now. If she's still low, I was told her abx protocol will be changed.

 

Questions-

 

1. She is on full doses of Zith, Mino and Bactrim. Drainage Tone and IMN-R for detox, and probiotic. On Zith for a little over a year. Mino and Bactrim since late spring. Is the WBC a result of abx? (from what I'm reading, Mino could be the culprit). If so, what does this mean exactly? Will changing to a different abx make a difference? or will she need to be weaned off? Are there physical consequences of low WBC as a result of abx?

 

2. She seems to be in a bit of a flare right now. I am terrified of taking her off any of the abx. She was doing so great up until about a week ago. I guess this isn't a quesion after all... but what would you do?

 

3. Could her current flare be a result of low WBC? If so, what do you do about that?

 

4. Could the low WBC be resulted from something other than the abx?

 

5. If we change her abx and she backslides, then what?

 

feeling scared. I thought we were doing so well here (aside from the minor recent flare), and suddenly I'm not feeling very confident at all. Thinking about what we went through last year just makes me want to run and hide. This spring holds so much promise for many little reasons, and I'm worried that they're all about to be crushed by PANS.

 

 

[MaryAW]

According to the Mayo Clinic a low WBC count can be due to:

 

•Viral infections that temporarily disrupt bone marrow function

 

If she is flaring, it may be that her immune system is engaged and is fighting off a virus. My suggestion would be to wait for the flare to end and retest the WBC count.

[sf_mom]

Treating Chronic Lyme et al is like a game of "Whack A Mole" per our LLMD. You pound one infection down and another one takes predominance. It could be viral or it could be a co-infection that impacts WBC like Erhichiosis.

 

http://en.wikipedia.org/wiki/Ehrlichiosis

 

For us, antibiotic rotations were always helpful when there was a slow and steady regression without obvious trigger. However, baseline improvement typically happened after initial herx response from these rotations. Noted herx often happened with 48 to 72 hours after rotation and increased symptoms that included rage behavior, OCD, tics. Once things settled from initial herx we often were able to picked up on cyclical die-off or increase in those particular symptoms out of no where. For us, it was typically every seven days.