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Does anyone know the mechanism by which a child is paradoxical in their response to antihistamine?


Benadryl, Claritin, Zyrtec... all seem to cause hyperactivity (ironically, i think the allergies themselves also cause hyperactivity). But it's a definite up tick with the anti-histamine on board.


We knew about this reaction before... but gave Claritin another shot... but no go... he's through the roof hyoer. Will try H2 blocker.


But what causes this unusual reaction?

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Benadryl made my non-PANDAS child want to jump out of a window. After having kids I too no longer tolerate these type of medications.


The dye can also set them off. Our Dr. has me even wash off the blue dye on Valacyclovir pills. Our kids are hypersensitive to many things.


I wonder if it has to do with their liver unable to break it down.

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