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FWIW DD4 had a bullseye last year (older DD has chronic Lyme) She was started on high dose amox 3x per day literally within an hour of me seeing it. (so thankful for my doc who called it in on a Saturday night for me) We treated for six weeks. She started to have symptoms (headache, lethargy) a couple of weeks after stopping abx and then tested CDC IGM positive with a Lyme specific band (39). We treated four months with cefdinir/zith and she seems to be symptom free. She has a high positive + ELISA but no WB bands, however has no symptoms so we are not treating. DD has an immune issue so that may be why the first treatment didn't work. it was very upsetting.

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