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Article comparing OCD and Ps


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hmmm...isn't kind of confusing that they said "separation anxiety" was more characteristic of PANDAS ocd but "separation anxiety disorder" was more prevalent in non-PANDAS ocd? Otherwise, I thought it was pretty good.

 

Results: PANDAS children were significantly more likely to present with separation anxiety, urinary urgency, hyperactivity, impulsivity, deterioration in handwriting, and decline in school performance during their initial episode of neuropsychiatric illness compared with children with OCD. Total tics and vocal tics were more severe in PANDAS children. Separation anxiety disorder and social phobia were more prevalent in non-PANDAS OCD children. Children with non-PANDAS OCD were significantly more likely to include others in their rituals. There were no significant differences between groups on demographics or severity of OCD.

 

Conclusions: Distinguishing clinical characteristics in PANDAS, which included urinary urgency, hyperactivity, impulsivity, and deterioration in handwriting, are linked to basal ganglia functions. These clinical characteristics will aid in the differentiation of PANDAS children for research and clinical purposes and ultimately advance our understanding and treatment of this disorder.

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hmmm...isn't kind of confusing that they said "separation anxiety" was more characteristic of PANDAS ocd but "separation anxiety disorder" was more prevalent in non-PANDAS ocd? Otherwise, I thought it was pretty good.

 

 

yes - it is confusing. I was able to get the full text article and it looks like kids with PANDAS had more frequent separation anxiety with their initial episode, but this did not turn into long-standing separation anxiety disorder.... but kids with OCD were more likely to have a separation anxiety disorder that evolved over time.

 

Here is what the discussion said about this in the article:

 

Symptoms of separation anxiety, inattention, mood swings, and oppositional defiant behavior were also significantly more common during their initial episode of neuropsychiatric illness in the children with PANDAS compared with children with non-PANDAS OCD. A significantly higher percentage of children in the non- PANDAS group (33%) met criteria for separation anxiety disorder compared with the PANDAS group (5%). However, significantly more children with PANDAS (74%) compared with non-PANDAS (39%) had separation anxiety as an associated symptom during their sentinel episode of neuropsychiatric illness. As PANDAS children had only a 5% rate of separation anxiety disorder, the finding that 74% showed separation anxiety during their initial episode of illness demonstrates a dramatic change in this symptom dimension during the onset of PANDAS. Separation anxiety and oppositional behaviors were described by Swedo et al. (1998) in their description of 50 children with PANDAS. Similarly, the sudden onset of severe, age-inappropriate separation anxiety was present in 42% (5 of 12) of PANDAS children in another study (Murphy and Pichichero 2002). Case studies also report sudden- onset separation anxiety, mood instability, and inattention in chil- dren with PANDAS (Perlmutter et al. 1998; Elia et al. 2005; Mabrouk and Eapen 2009).

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