problemsolver Posted July 22, 2011 Report Share Posted July 22, 2011 ASO was 7 Reference Range is <150IU/ml EBV No EBV antibody detected DNASE B Antibody <50 Reference Range <187 U/ml Now here's one I'm not sure what to do with, HHV-6: IgG 2 years ago was 1:320 Reference Range was <1:80 IgG this year is 1:160 Reference Range is <1:10 HOW DO THESE HHV6 TITERS COMPARE, AS THE REFERENCE RANGE IS DIFFERENT? HAS IT INCREASED OR DECREASED? DO WE NEED TO TREAT IT? IgM was <1:40 last time, <1:20 this time ON HHV6. How do the numbers look to you? Link to comment Share on other sites More sharing options...
JAG10 Posted July 22, 2011 Report Share Posted July 22, 2011 I'm not sure about the HHV6, sorry. I just wanted to mention something about the strep antigen titers; some children with pandas have a hyper-immune system and some have a hypo-immune response. Ironically, either can show immune deficiencies. Not sure about the science behind that, but my girls have run very high titers in the past, yet were low Total and sub-class specific IgG and IgA, so IVIG has really helped her a lot. Has your DS had an immune panel work-up? Link to comment Share on other sites More sharing options...
problemsolver Posted July 22, 2011 Author Report Share Posted July 22, 2011 I'm not sure about the HHV6, sorry. I just wanted to mention something about the strep antigen titers; some children with pandas have a hyper-immune system and some have a hypo-immune response. Ironically, either can show immune deficiencies. Not sure about the science behind that, but my girls have run very high titers in the past, yet were low Total and sub-class specific IgG and IgA, so IVIG has really helped her a lot. Has your DS had an immune panel work-up? No, he has had EBV, CMP, CBC, HHV6, ASO and AntiDNAse B... what did we miss, and, do we need another blood draw for it? Link to comment Share on other sites More sharing options...
JAG10 Posted July 22, 2011 Report Share Posted July 22, 2011 An immunologist may look at total IgG, IgA, Ig subclasses, C3D complexes, celiacs and more. If you were to ever consider Ivig, your boy would get "passive immunity" for some of the viruses he has yet been exposed to such as EBV and some hepatitis, so he would no longer be IgG negative for those viruses. These tests reflect more the health of his immune system rather than specific viruses he has been exposed to in the past. Link to comment Share on other sites More sharing options...
problemsolver Posted September 22, 2011 Author Report Share Posted September 22, 2011 An immunologist may look at total IgG, IgA, Ig subclasses, C3D complexes, celiacs and more. If you were to ever consider Ivig, your boy would get "passive immunity" for some of the viruses he has yet been exposed to such as EBV and some hepatitis, so he would no longer be IgG negative for those viruses. These tests reflect more the health of his immune system rather than specific viruses he has been exposed to in the past. What are the specific names of all of those tests you're talking about? Do you have an example you could email me? Dave Link to comment Share on other sites More sharing options...
P_Mom Posted September 22, 2011 Report Share Posted September 22, 2011 (edited) The HHV titers are decreasing. Personally, I would leave it alone as it has decreased. Edited September 22, 2011 by P.Mom Link to comment Share on other sites More sharing options...
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