Vaccine-induced Strep Pneumonaie antibodies

[JAG10]

Is this something ALL of our children have in common? Failing a majority of the 14 serotypes? Has anyone's child had a healthy response to the whole or almost the whole panel? (can you please post if your child had a normal response?)

 

So, in some cases, our kids over-produce antibodies to strep antigens (ASO, aDNAseB) but fail to produce antibodies to all 14 serotypes?? Is that right?

 

Has anybody had other vaccine responses tested other than strep pneumonaie? Should we be looking at other vaccine responses?

[mom love]

Our doctor told us that the child will pass if they pass at least 7 of the 14. Our daughter passed about 7 or 8 of them. She has had all her baby vaccines but will never get another vaccine while I am alive, so she didn't have the booster if there is one.

[philamom]

H. Influenzae Type B Antibody IGG

 

My daughter's level of protection is low.

[Kayanne]

No, not all of our children have this in common. MY daughter passed the 7. She did have all of her prevnar shots. We have not seen any adverse effects from vaccines in our house.

[mama2alex]

Our ds, who was fully vaxed with prevnar, failed most of the s. pneumoniae titers and eventually, after much hesitation, was given the pneumovax (the adult version of prevnar). He then passed, but still had a few strains he was non-responsive on. Also, he is fully vaxed for pertussis and when we tested his titers, he had zero response - no immunity whatsoever.

[P_Mom]

Jill,

 

My older son has a healthy s. pneumonia response (passing all 7 vaxed for with flying colors and then even having more strains covered)....my younger sons was considered a bit weak,(had a response to all 7 vaxed for ,but, numbers on the lower end...also has some others present that he wasn't vaxed for) but he is still acceptable. This is why their immunologist isn't concerned at this point about their lowish IGG and IGA. We track every 6 months for now.

 

We also had other vaccine responses tested for. Chicken pox, rubella, pertussis, diptheria, tetnus....they both had protective antibodies to everything tested for. Both of them had a high response to Rubella, which is interesting to me...I wonder if this Rubella viral antibody could be a problem?? My younger son never even got the booster shots (thank God) and his rubella is still high. (and all his other levels are good...so, he didn't even need the booster) The Pertussis for both was high, but, they had both contracted Pertussis a month or so before tested...so, that was to be expected. They were both fully vaxed as babies and should not have contracted Pertussis...but they both did. Perhaps had we checked before, they may have had no Pertussis response. Who knows. Either way, their bodies responded normally to the Pertussis and made more than enough antibodies to defeat the illness. They will always have Pertussis antiboidies now. I spoke with Dr. Latimer and she said she is seeing kids getting Pertussis more often. She thinks the vaccine (the Pertusis part) could be a failure. Again, who knows.

 

Neither son over produced strep antibodies...they rose with infection, but, never got really high like some on here. The highest we were able to catch was a 185 ASO in my older son. His baseline is about 70-80. My younger sons highest was 103...his baseline is about 20. But, we never got a draw in exacerbation...we know those valued would have been higher, but, based on where they were 3 months after strep, we don't think they ever got crazy high.

[norcalmom]

Failed all but two - and one of them was at the very lowest passible number. For some he created none at all.

 

Recently found VERY high IgG for mycoplasma. but no IgM (which would indicate active infection). This is another pneumonia...so gotta wonder if its connected somehow.

 

Also had slightly low overall igG and Subclass 1 deficient.