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http://vaccinepapers.org/al-adjuvant-causes-brain-inflammation-behavioral-disorders/ "...the study found that the lowest dose (200 mcg/Kg) was the most toxic! For many outcomes, the 400 and 800 mcg/Kg dosages had no observable adverse effects, but the 200 mcg/Kg dose did. Crepeaux (paper): Non-linear dose-response of aluminium hydroxide adjuvant particles: Selective low dose neurotoxicity The low toxicity of the higher dosages appears to be a consequence of dosage-dependent inflammation at the injection site. The high dosages caused intense inflammation at the injection site, forming “granulomas”. The 200 mcg/Kg dosage did not produce granulomas. Granulomas are hard nodules in tissue produced in response to injury, infection or foreign substances. Its a way the body “walls off” injured tissue and prevents the spread of infection or toxins. The granuloma appears to provide protection from Al adjuvant toxicity. The granulomas prevented the Al adjuvant particles from leaving the injection site. This explains why the 200 mcg/Kg dosage affected the brain and behavior, while the higher dosages did not. This suggests that it is more dangerous and harmful to administer numerous small injections of Al adjuvant, compared to a large single injection capable of inducing a granuloma." "According to the US vaccination schedule recommended by the CDC, infants are urged to receive the following (maximum) dosages of Al adjuvant: Birth: 74 mcg/kg (250 mcg for 3.4 kg infant) (Hep B only) 2 month: 245 mcg/kg (1225 mcg for 5 kg infant) (Hep B, DTaP, HiB, pneumococcal, polio) 4 month: 150 mcg/kg (975 mcg for 6.5 kg infant) (DTaP, HiB, and pneumococcal) 6 month: 153 mcg/kg (1225 mcg for 8 kg infant) (Hep B, DTaP, HiB, pneumococcal, polio) Since each Al-containing vaccine is not given in exactly the same location (and are often given on different limbs), each vaccine may provide a “low” dose that does not form a granuloma and hence deposits transportable Al adjuvant. Human infants are likely receiving Al adjuvant in numerous small doses that can be transported to the brain."
Very interesting reading from AoA Contributing Editor Teresa Conrick: http://www.ageofautism.com/2016/12/cdc-denying-harmful-human-vaccine-consequences.html "A particularly notable finding in our study is the 900% increase in noninvasive pediatric vaccine-related isolates that was associated with serotypes 19A...serotype 19A frequently recovered from middle ear fluid specimens. ● It is noteworthy that serotype 19A—the original multidrug-resistant serotype reported from South Africa in 1978 —emerged in the United States after the introduction of PCV7 in 2000, and many of these isolates are multidrug resistant." "Vaccination with PCV-7 resulted in a shift in bacterial community composition and structure, with an increase in presence or abundance of several anaerobes, such as Veillonella, Prevotella, Fusobacterium, and Leptotrichia species; gram-positive bacteria, such as Actinomyces and Rothia species, and nonpneumococcal streptococci; and gram-negative Neisseria species…. Together with S. pneumoniae nonvaccine serotype replacement, these effects may further jeopardize the net health benefit of vaccinations with PCV.” http://www.ageofautism.com/2014/06/the-human-microbiome-evolution-of-vaccine-exposure.html Vaccination is likely to have important consequences for the NP microbiome. Current pneumococcal vaccines are directed against multiple serotypes thus potentially eliminating these from the microbiome. Based on observations on this and other vaccines, new organisms are expected to move into the empty niches created by vaccine elimination of organisms. Thus the structure of the microbiome is altered by vaccines. The unintended consequences of this alteration remain to be seen. It seems very possible that if the microbiome takes a hit, like mercury exposure or immune manipulation via vaccination, the more we may see the immune system diseases rapidly rise. Autism and PANDAS/PANS and other immune-damaged diseases deserve huge concern and true research." http://www.ageofautism.com/2014/04/autism-does-mercury-modulate-the-microbiome.html#more "... here are studies showing how it is the microbiome, not genes, that will lead the way in helping so many stricken with these symptoms: • That veil is only very recently being lifted with respect to a potential role for autoimmunity in neuropsychiatric disorders. This shift has occurred as evidence accumulates to support the idea that dysregulated cross-talk between the brain and the immune system is an important contributor to the pathogenesis of conditions as diverse as schizophrenia, mood disorders, autism spectrum disorders (ASDs), obsessive-compulsive disorder (OCD), Tourette syndrome and other tic disorders, attention-deficit hyperactivity disorder (ADHD), anorexia nervosa, narcolepsy, posttraumatic stress disorder and myalgic encephalomyelitis/chronic fatigue syndrome (CFS).[4,5] In addition, intriguing new evidence lends support to the possibility that not only the microbes associated with infectious episodes but also the bacteria of the gut microbiome can foster the production of brain-reactive autoantibodies, and that these microbe-induced antibodies provide the critical link between infection and neuropsychiatric disorders. • ….Eventually, as more pathogens are incorporated into the microbiome and levels of dysbiosis increase, people begin to present with symptoms characteristic of an autoimmune or inflammatory diagnosis......There is increasing evidence that autoimmune diseases run in families due to the sharing of common microbes.... The microbiome a child develops is a direct reflection of those harbored by the mother and close relatives. Microbes are introduced by a multitude of sources including the placenta, sperm,egg, breast milk, and vaginal canal. …. Autoimmune diseases are more likely passed in families due to inheritance of the familial microbiome than inheritance of Mendelian genetic abnormalities.” "Note that the above study refers to "regressive-type" autism as a disease. I have watched my own daughter suffer for years -- infections, pain, neuropsychiatric symptoms related to PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections) and an autoimmune diagnosis shown by antinuclear antibodies. Since 1938, those with the symptoms called “autism” have been put on a spectrum, from low functioning to high functioning. It is very possible that their functioning had everything to do with a dysfunctional microbiome." Here is a good video by Stephanie Seneff on the association between glyphosate, vaccine constituents, gut bacteria and autism: https://www.youtube.com/watch?v=o3P6wVUH0pc