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Hello! My DS8 was diagnosed with Lyme last Spring. He was also diagnosed with PANS triggered by the Lyme. For the last 12 months he's been on a combo of Zithromax and Omnicef and doing wonderfully. I am happy to report that he hasn't had much in the way of symptoms for the last 6 months and absolutely no symptoms for the past 3 months. He was never diagnosed with co-infections (not really any symptoms and lab tests all came up negative). We feel pretty comfortable that he is ready to move on to the next stage of treatment. Our LLMD feels that slow and steady wins the race with Lyme treatment. At the end of April, she would like us to add Tindamax, twice a week to rule out (or eliminate) the cyst form. If all goes well, we could try stopping all abx by the start of summer. Our LLMD doesn't think the Tindamax will create a huge issue for my son. Besides the Lyme, he is a very healthy child and hasn't had any issues with detox so far. I've come across many unpleasant Tindamax stories and it has started to make me a bit nervous. I've heard detox is key. I'd like to be as prepared as possible, so I'd love to hear your recommendations and advice! Just in case anyone is interested, here's what we've had great success taking since the start of our treatment: FloraMyces (am) Metagenics UltraFlora Synergy (pm) Vitamin D- started with 1000 up to 2000 Multi-vitamin Nordic Naturals Children's DHA Thankfully, we've never had a yeast issue using this combo of probiotics. Once we go off antibiotics, our LLMD plans to work in some naturals for awhile. I know she uses something for biofilms too. Thanks!!