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Has anybody read the book Brain Maker by David Perlmutter? http://smile.amazon.com/Brain-Maker-Microbes-Protect-Brain%C2%96/dp/0316380105/ref=sr_1_1?ie=UTF8&qid=1443638847&sr=8-1&keywords=brain+maker In chapter 9 he talks about a PANDAS (Tourette's?) kid (Christopher)...I'm not sure Perlmutter has a great grasp on PANDAS (since in his mind, it's a form of Tourette's). However, what he had to say was interesting. He treated this kid (mainly tics, didn't mention other symptoms, so maybe he was really TS, not PANDAS/PANS, with an enema enriched with probiotics, with good results. This book does have some interesting points btw...definitely parts I don't agree with (such as he claims it's been proven that vaccines aren't a cause autism), and IMHO he blames too many problems on antibiotics (and not necessarily the infection for which the antibiotics were prescribed, or the Tylenol which was likely given with the infection/antibiotics). But, nonetheless, he brings up some interesting ideas. Also, has anybody heard of using pro-biotic enriched enemas? It's definitely an interesting idea.