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We recently had an OAT and IgG tests run for my 6 year old son who has Tourette’s (and OCD / Anxiety). OAT results showed elevated Arabinose, Lactic and Hydroxyhippuric. It also showed extremely low Ascorbic (vit C). The IgG test showed high sensitivity to Wheat. Wheat Gluten, Gliadin and Whey. With moderate sensitivity to Cassein, Cheese and cow’s milk. I would be really interested to hear if anyone who has done similar tests / had similar results and what you have done since them. I’ve not been able to find anyone in the UK who has much background in Tourette’s and the gut/brain connection, so feel we are doing this a bit blind. Our son is taking a magnesium and omega 3 supplement and are now starting a gluten free diet. A herbalist has given us an additional supplement for the yeast infection (using camomile and a few other herbs). I was interested in some of the posts on histamine – and looking at trying to decrease DAO, but don’t really know whether this is also something to try. Any advice, thoughts, input would be great.
Thank you for taking the time to read my post. Since December 17th, 2016, suddenly I have been experiencing episodes of intense anxiety, depression, depersonalization, disassociation, panic etc. These usually happen in the evening, every other day, and last for awhile (from hours to days). At the same time, there is a lot of brain fog, fatigue, and I just know there's something not right in my head, mentally. And I am very certain that it is caused by something physical (hence, why I did lyme testing). I don't have any physical symptoms such as joint aches, but in the beginning I had a constant back of the skull pressure type of headache. Recently, I took a blood test for Lyme. Here are my results. ELISA: 0.92, which is in the EQUIVOCAL range. Western Blot, Reactive Bands: 41, 58, 66, 93 (IgG) and 41 (IgM) Right now, my doctor is saying to take doxycycline 100mg twice daily for 30 days. Then after the 30 days, I will do a second western blot. Do you guys have any advice what steps I should do from here? Thanks again. REFERENCE RANGE: <=0.90 INTERPRETIVE CRITERIA: <= 0.90 NEGATIVE 0.91-1.09 EQUIVOCAL >= 1.10 POSITIVE The use of purified VlsE-1 and PepC10 antigens in this assay provides improved specificity compared to assays that utilize whole cell lysates of B. burgdorferi, the causative agent of Lyme disease, and slightly better sensitivity compared to the C6 antibody assay. As recommended by the Food and Drug Administration (FDA), all samples with positive or equivocal results in a Borrelia burgdorferi antibody EIA (screening) will be tested using a blot method. Positive or equivocal screening test results should not be interpreted as truly positive until verified as such using a supplemental assay (e.g., B. burgdorferi blot). The screening test and/or blot for B. burgdorferi antibodies may be falsely negative in early stages of Lyme disease, including the period when erythema migrans is apparent. Test Performed at: Focus Diagnostics, Inc. 33608 Ortega Highway San Juan Capistrano, CA 92675-2042 H J Batterman MD REFERENCE RANGE: NEGATIVE As per CDC criteria, a Lyme disease IgG immunoblot must show reactivity to at least 5 of 10 specific borrelial proteins to be considered positive; similarly, a positive Lyme disease IgM immunoblot requires reactivity to 2 of 3 specific borrelial proteins. Although considered negative, IgG reactivity to fewer specific borrelial proteins or IgM reactivity to only 1 protein may indicate recent B. burgdorferi infection and warrant testing of a later sample. A positive IgM but negative IgG result obtained more than a month after onset of symptoms likely represents a false-positive IgM result rather than acute Lyme disease. In rare instances, Lyme disease immunoblot reactivity may represent antibodies induced by exposure to other spirochetes. Test Performed at: Focus Diagnostics, Inc. 33608 Ortega Highway San Juan Capistrano, CA 92675-2042 H J Batterman MD
My daughter was diagnosed with PANDAS in May and since then I have found this forum and spent hours reading through the posts gaining as much knowledge as possible. Thank you for all of the great information and support you provide! My daughter was diagnosed at seven, we believe it to be new onset and we started treatment right away with high dose Augmentin. She is doing extremely well, I would say 95% back to herself which I am so thankful for! However, during her workup, it was discovered that she has low pneumococcal titers, only 1 out of 23 in range. The rest of her immune work up was within normal limits (IGg, IGm etc.) Now her doctor wants her to get the pneumovax and retest her titers in 6 weeks which I am very hesitant to do. I also want to remark that up until now she has been very healthy other than reoccurrent ear infections as a baby that she outgrew after a year of age. I am not against vaccines, she received all the normal scheduled vaccines thus far,but I am concerned that it may exacerbate her PANDAS again. I have read through all of the past posts on this forum and it sounds like there was a bit of debate on this issue. Those topics seemed to be from 2009-2011 and I was wondering how things turned out and if the parents who did choose to vaccinate had a positive and sustained rise in the follow up titers. It seems as if there is a subset of kids on this forum with questionable immune deficiencies. I would appreciate any advice on this as well as long term treatment plans. We are just kind of taking it day by day and praying for the best. She is still on the Augmentin but a lower dose now, I would like to try to take her off of it as it is upseting her stomach, causing her to lose her appetite and her teeth have begun to stain as well. Has anyone been able to wean there kids off the antibiotics without the symptoms returning? Sorry so long! Thank you in advance!