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I'm wondering if anyone here has info/experience with very low c3 and c4 immune complement levels? Dd has been struggling with new and different symptoms since July - they ran these two levels and both are close to zero. Lupus has come up in discussion - her ANA panel came back negative, but her direct bilirubin, albumin, urea, creatinine, ldh are all elevated which is new for her. Gluten panel also came back fine (checking for celiac). ANY information is so appreciated! We are in a frantic bind trying to figure out what to do/where to go next...