Report need advice and support in PANS / PANDAS (Lyme included) Posted May 1, 2016 · Edited May 1, 2016 by whyPANDAS just started Rituximab for son, who has long history of tick borne illnesses. and PANDAS. He is 21. He has been severely agitated for a couple months since stopped antibiotics and IVIG. He is blown up by Prednisone. Mayo Clinic recommended this but seems not to acknowledge possibility that TBI may still be present. Son having breathing problems...wonder if it is Rituximab, Prednisone or may Babesia which has reared its head.when he is immune suppressed by Prednisone. Very upset and don't know where to turn. Dont know anyone whose child has had rituximab. Would appreciate any communication.