Report CVID and Pandas/Pans/Lyme in PANS / PANDAS (Lyme included) Posted November 28, 2011 if ivig helped a ton, and lyme treatment is NOT helping, I would just guess that maybe it wasn't lyme? I know, I will be hated for saying that by some. I still believe that there are people being treated for lyme "clinically" that fit the wastebasket diagnosis....no positive tests, just "clinical" lyme diagnosis based on neuropsych symptoms only, when it might not be lyme. EVEN WITH positive Igenex. I have looked at Igenex, and still think that it is picking up +'s on some bands that are not actually lyme, but yet it's being called positive for lyme. my personal feeling at this point, is that in some kids, Pandas triggers an autoimmune response which then comes and goes with infections. I think in other cases, while there may still be an infectious trigger, it is "THE TRIGGER" that switched on the gene in predisposed people (predisposed to having ocd, tics, etc...).