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EAMom

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  1. Like
    EAMom got a reaction from mama2alex in Sacramento Observer article on CDC Whisteblower   
    Also posted on a separate thread, here is a really good interview w/Dr. Wakefield.
     
    The CDC whistleblower is discussed.
  2. Like
    EAMom reacted to mama2alex in Vaccine Exemptions in CA   
    SB277 just passed the CA Senate and now goes to Governor Brown's desk. If you live in CA and don't want the government forcing you to vaccinate your child (and your grandchildren!) with whatever they say, whenever they demand it, PLEASE write and call Gov. Brown! This bill will not allow any child missing even one vaccine to attend public or private school, and it will not allow homeschoolers and Independent Study kids into a classroom of any sort, even if its through your homeschool program.
     
    Governor Jerry Brown
    c/o State Capitol, Suite 1173
    Sacramento, CA 95814
     
    Ph: 916-445-2841
    Fax: 916-558-3160
  3. Like
    EAMom got a reaction from mama2alex in Vaccine Exemptions in CA   
    Former Merck drug rep on #SB277
    https://m.youtube.com/watch?v=nOMnLZoFcZY
  4. Like
    EAMom got a reaction from kim in Rheumatic disorders developed after hepatitis B vaccination   
    Yes, when Senator Anderson asked Pan about the Hep B, Pan ending up not answering the question and started a talking about measles at Disney (again).
     
    So, I found out from somebody that works at a hospital that they do know which moms are Hep B positive and which aren't...don't know if this is true at all hospitals.

    I should say that the legislators (and their people) are sorely uninformed. Basically the legislators (aside from a couple, like Anderson) are getting spoon fed info from Pan, and that's all they are processing. I had a meeting with an aide of one of the CA senators. Her stance was that vaccines are very well tested and completely safe. She simply couldn't understand why anybody would NOT want to give a baby Hep B, even if that infant was at very low risk for infection (eg Hep B negative mom).

    I should also add that this person (who is working closely with the senator, and we weren't allowed to actually talk to the senator) was so uninformed that she thought a Hep B positive child would be allowed to go to school AFTER that child received a Hep B vaccine. So these people (who don't even understand that vaccinating a Hep B positive child for Hep B would be completely pointless)...the ignorance is frightening and these are the people in control.
    .


  5. Like
    EAMom reacted to kim in Rheumatic disorders developed after hepatitis B vaccination   
    ajcire, That type of information may be imperative as choice is being threatened in multiple states (or lost already) in the case where you might want to try to get a medical exemption for vaccination. History of advese events and immune function testing results are going to be valuable for those who have it. The problem is going to be over coming the attitude that any immune dysfunction is going make it all the more reason that your child should be vaccinated with anything/everything that they can create a response to, no matter how unnatual (or inflammatory) the response is. Personally, I'm of the opinion that constant manipulation of the infant immune system is wrecking havoc on at least some of our children. This is not to dismiss genetics or other environmental insults. I also have full respect for any one choosing a particular vaccine where they feel the reward out weighs the risk. Unfortunately, it seems parents are going to have to be the ones who convince the medical "authorities." http://www.ncbi.nlm.nih.gov/pubmed/20531967 Biologics. 2010 May 25;4:75-81. Hepatitis B virus and Homo sapiens proteome-wide analysis: A profusion of viral peptide overlaps in neuron-specific human proteins.
  6. Like
    EAMom reacted to pr40 in martial arts in place of cbt   
    Recent post on CBT made me think about this:
     
    we tried cbt and had some success. hubner's book was more helpful in forming a strategy BUT both failled in creating a habit. For habit forming -- learning how to control oneself -- martial arts were, by far, most successful.
    ds started when 6 and 1/2. he was in a flare at the time.
    after a year, we have a little jedi.
    there is no talk ever about fighting and violence. martial arts is about self-defense and, by and large, movement. if you have no experience, think of it as a form of dance choreographe.
    i would recommend it over CBT anytime
  7. Like
    EAMom reacted to kim in Vaccine Exemptions in CA   
    eamom,
     
    I think the original link to your last post was here
    http://healthimpactnews.com/2013/study-flu-vaccine-causes-5-5-times-more-respiratory-infections-a-true-vaccinated-vs-unvaccinated-study/
     
    a statement from that article
     
    The authors play with statistics in this study by using assumptions about whether people actually had diseases, because there were many reported instances that couldn’t be verified. They came up with a relative risk of 4.4. In any case, relative risk is actually a meaningless statistic here, because it requires that exposure to the causative agent be known, which it clearly wasn’t in this study
    I was trying to figure out this case control study on the effectiveness of vaccinating a pregnant mom with the pertussis vax. I can find very little but here's one

    http://www.gsida.org/wp-content/uploads/2014/09/A-Case-Control-Study-to-Estimate-the-Effectiveness-of-Maternal-Pertussis-Vaccination-in-Protecting-Newborn-Infants-in-England-and-Wales-2012-2013.pdf

    case-control study was undertaken in England and Wales between October 2012 and July 2013.
    Cases were infants aged <8 weeks at onset with pertussis infection tested by real-time polymerase chain reaction
    or culture. Family doctors of each case were asked to identify healthy infants born consecutively after the case in
    each practice, to act as controls. Fifty-eight cases and 55 controls were included in this study. Odds ratios (ORs)
    were calculated for the association between maternal vaccination and infant pertussis infection. The vaccine effec-
    tiveness (VE) was calculated as 1–OR. This was adjusted for sex, geographical region, and birth period. Results.

    Mothers of 10 cases (17%) and 39 controls (71%) received pertussis vaccine in pregnancy. This gave an
    unadjusted VE of 91% (95% confidence interval [CI], 77%–97%). Adjusted VE was 93% (95% CI, 81%
    –97%)
    .Conclusions. Maternal pertussis vaccination is effective in preventing pertussis infection in infants aged <8
    weeks and may be considered in other countries experiencing high levels of pertussis notifications.

    The strength of this study and the findings aren't particularly reassuring (10 out of 58 infants of vaccinated moms still had diagnosed pertussis) in my limited understanding. This is not even taking into consideration the effects on the mothers immune system, or the infants.



  8. Like
    EAMom got a reaction from rowingmom in Autism Occurrence by MMR Vaccine Status Among US Children With Older Siblings With and Without Autis   
    Stephanie Seneff knows more about this too

    She written about multiple toxicants in the environment affecting the CYP enzyme activity. Most notable is glyphosate, the active ingredient in Roundup, which is working synergisticially with vaccines to cause harm, in her opinion. It has been shown to reduce CYP enzyme activity in plants, microbes and the liver of rats.


  9. Like
    EAMom got a reaction from kim in Vaccine Exemptions in CA   
    More original antigenic sin??
     
    "More concerning than the fact that the flu vaccine is not effective, and therefore cannot be used as a reason to justify flu vaccine injuries and deaths, is the research showing that the vaccine can actually cause people to be more susceptible to the flu, or suffer worse symptoms if they contract the influenza virus.
     
    This phenomenon where the flu vaccine can actually make the flu worse was originally observed in mass in Canada during the 2008-2009 flu season. Researchers studied the issue for the next couple of years and concluded that the flu vaccine did in fact increase the severity of flu symptoms among those who were vaccinated (see: Study finds flu shot really did make people sicker.)
     
    The same issue was studied in Hong Kong in 2012 by comparing a group of people vaccinated with the flu vaccine against a group that used a placebo. The researchers found that those who received the flu vaccine suffered 5.5 times more incidents of similar diseases (see: Study: Flu Vaccine Causes 5.5 Times More Respiratory Infections A True Vaccinated vs. Unvaccinated Study.)
     
    In 2013, a study conducted by microbiologist Dr. Hana Golding of the Center for Biologics Evaluation and Research at Bethesda in Maryland showed that pigs vaccinated against one strain of influenza were worse off if subsequently infected by a related strain of the virus (see: Vaccination may make flu worse if exposed to a second strain.)"
     
    - See more at: http://healthimpactnews.com/2014/government-pays-damages-to-vaccine-victims-flu-shot-most-dangerous-with-gbs-and-death-settlements/#sthash.JG1fUBwu.dpuf
  10. Like
    EAMom got a reaction from kim in Vaccine Exemptions in CA   
    "Scientists studying flu vaccines have identified ways to overcome an obstacle called "original antigenic sin," which can impair immune responses to new flu strains.
     
    Original antigenic sin (OAS) is a situation where the immune system is fighting with obsolete weapons and has trouble adapting. After encountering one viral strain, and then a new one that is related to the first, the immune system can respond by making antibodies against the first strain, resulting in a less effective defense."
     
    http://news.emory.edu/stories/2012/08/flu_vaccines_original_sin/campus.html
     
     
     
    ^^ so I'll bet the non-vaccinated kids with whooping cough can fight it off better if they do get infected, so maybe it doesn't get to the diagnosed/severe stage.
  11. Like
    EAMom reacted to nicklemama in Vaccine Exemptions in CA   
    I am in a parenting board and there is a mom on there who is militantly pro vaccination and I've had words with her more than once. Yesterday, she said she was against the Calif bill. I have asked her if she would mind sharing why. We will see if I get an answer.
  12. Like
    EAMom reacted to kim in Vaccine Exemptions in CA   
    I'm truly sick and so disappointed in the people who are elected to do this job. http://www.mercurynews.com/health/ci_28007m382/california-vaccine-legislation-advances-senate-judiciary-committee
     
    California vaccine legislation advances in Senate Judiciary Committee
     
    * * * * * * * * *
     
    http://sanevax.org/hpv-vaccines-precautionary-principle-advised/
     
    This video adds insult to injury today
     
    HPV Vaccines: Dr. Sin Hang Lee, Director of Milford Medical Laboratory, explains the potential consequences of non-b conformation foreign DNA combined with aluminum salts discovered in Gardasil. Due to the unknown toxicity of this new chemical compound, he recommends that governments around the world apply the precautionary principle and halt HPV vaccination programs until research is done to determine how toxic this new chemical compound is. (The following video is recorded in English, subtitled in French.)
  13. Like
    EAMom got a reaction from philamom in Pediatrician Won't Do Lab Work   
    this might also be useful http://iocdf.org/pandas/
  14. Like
    EAMom reacted to nicklemama in Pediatrician Won't Do Lab Work   
    If you have been pushing for a year with this doctor, you need to move on. If I had waited for my pediatrician to test my son 5.5 years ago, I'd still be here waiting. Find a doctor that understands and treats PANS. You don't have to jump to IVIG without testing. Test for lyme too.
  15. Like
    EAMom reacted to kim in Vaccine Exemptions in CA   
    eamom,
     
    I hate even going into the HPV vaccine cause I'm in serious stroke territory. I was going to respond to your earlier question by saying that a total guess would be that there is some cross reactivity going on btwn the vaccine and different strains that an individual may be carrying prior to vaccination (as opposed to serotype replacement which has been a problem with vaccines like PCV 7 now 13). The more I thought about what I was going to say, the more I thought, "that does sound like "original antigentic sin." So i did what I do and up popped this
     
    http://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2014-06/HPV-02-Luxembourgpost.pdf
     
    page 28
     
    I only saw the words, don't have any idea what they are referring too there.
     
    edit....as soon as I lose my job altogether, get divorced and my kids totally stop trying to communicate with me, i'll try to figure more of that out unless you want to take it over!
  16. Like
    EAMom got a reaction from kim in Vaccine Exemptions in CA   
    Oh...and as far as being "safe" to give while pregnant, this is what they looked at:
     
    "Main Outcomes and Measures Primary outcomes were maternal and infant adverse events, pertussis illness, and infant growth and development until age 13 months. Secondary outcomes were antibody concentrations in pregnant women before and 4 weeks after Tdap immunization or placebo, at delivery and 2 months postpartum, and in infants at birth, at 2 months, and after the third and fourth doses of DTaP."
     
    ...so we don't know if this dTap during pregnancy would increase the risk of autism, allergies, of any other neuro/immune disorders bc they only followed the baby for 13 mo!
     
    Yeah, and as far as cocooning...vaccine recommendations (vaccinate mom, caregivers, everybody) doesn't jive with current research/baboon study. I find these recommendations very troubling.
  17. Like
    EAMom reacted to kim in Vaccine Exemptions in CA   
    eamom,.
     
    What I found stunning was the fact that the study included so few women.
     
    Forty-eight pregnant women aged 18 to 45 years received Tdap (n = 33) or placebo (n = 15) at 30 to 32 weeks’ gestation, with crossover immunization postpartum
     
    Yet, that was the study the Calif. dept of public health cited. They know you have to use these things in large populations to get any kind of reliable safety data (not that we'll know what it truly looks like anyway). Munoz says that herself in the interview.
     
    http://medicalresearch.com/author-interviews/tdap_vaccine_during_pregnancy_safety_and_efficacy/5128/
    excerpt near the bottom
     
    MedicalResearch.com: What recommendations do you have for future research as a result of this study?
    Dr. Munoz: We did not aim to study the efficacy of vaccinating pregnant women in preventing infant pertussis infection. Therefore, larger studies to document the safety and efficacy of Tdap vaccination during pregnancy are needed.
     
    The next question that I have is how many of the moms of the infants that were hospitalized (77) or diagnosed during the outbreak that occured Jan-April 2014 had received the vaccine?
     
    It looks like the rec to vaccinate pregnant moms was added in February of 2013
     
    http://www.acog.org/Resources-And-Publications/Committee-Opinions/Committee-on-Obstetric-Practice/Update-on-Immunization-and-Pregnancy-Tetanus-Diphtheria-and-Pertussis-Vaccination
     
    I wonder if this is the kind of research that "Hillary grandma knows best," spends her free time looking at.
     
    again, if you want to yourself right off, start reading about the infant and maternal programming naturally here.
    http://www.beyondconformity.org.nz/hilarys-desk/vaccines-and-neonatal-immune-development. Engaging the immune system repeatedly with vaccines that force an unnatural immune respone takes on a whole new meaning. I don't want the government owning any childs immune system.
  18. Like
    EAMom reacted to kim in Vaccine Exemptions in CA   
    after reviewing again, I think this is my take away
     
    > A crucial antigen from natural infection is Adenylate cyclase toxin (ACT)
    >No ACT with aP vaccine very little with wP vaccine
    >Body does not make ACT antibodies on reexposure because it was primed with vaccine antigens (the original sin)
    >In vaccinated animals colonization is not prevented upon reexposure, pertussis capable of mutating because it was not cleared and infected capable of transmitting.
    >Pertactin free strain may not necessarily make it harder to clear, it may just make the vaccine less effective. The ability of the strain to infect vaccinated as opposed to naturally infected (who recovered) individuals and mutate would have been the sin committed by the original sin of prompting a suboptimal immune response. That last sentence is my own jargon.

    On the pregnancy issue. I decided to see what I could find in Califonia on what happened to infants during recent outbreaks. Vaccinating every pregnant female with each pregnancy seems radical.

    http://www.cdph.ca.gov/HealthInfo/discond/Documents/CDPH%20pertussis%20health%20alert%20May%2016%202014.pdf

    2nd paragraph

    Under 3 mos. old? Ok, so we'll vaccinate the kids six times, the health care workers, dads, aunts, uncles, care givers, librairians, butchers, bakers and candlestick makers and then we'll vaccinate the pregnant mom. Oh, and if you didn't catch her while pregnant get her before she goes home.

    Be sure to read on the clickable about the "no adverse events," of vaccination during pregnancy. Notice the first name on the study
    then read here

    http://medicalresearch.com/author-interviews/tdap_vaccine_during_pregnancy_safety_and_efficacy/5128/

    Tdap Vaccine During Pregnancy: Safety and Efficacy
    Posted on May 16, 2014

    Flor M. Munoz, MD Department of Pediatrics Department of Molecular Virology and Microbiology Baylor College of Medicine, Houston, Texas MedicalResearch.com Interview with:
    Flor M. Munoz, MD


    So the baboon study doesn't apply to humans or they are confident that the vaccines (mom and then the series that starts at 2mos) will result in less severe illness in infants or they just don't know what else to do?????? How about massive media coverage to tell what is known or unknown at this point and giving everyone a heads up to try to protect those infants from people who appear to have a cold or full blown whooping cough?
     
    Does this seem ok to anyone?
  19. Like
    EAMom got a reaction from kim in Autism Occurrence by MMR Vaccine Status Among US Children With Older Siblings With and Without Autis   
    And more (copied from another forum) on African Americans (who are conveniently under represented in this study):
     
    Mayo Clinic Discovers African-Americans Respond Better to Rubella Vaccine - Findings May Help Make Immunizations More Effective and Safer
     
    This Merck vaccine immunologist consultant says that genetics cause different responses - and perhaps safety - in African Americans, Caucasians and Hispanics. That the "one size fits all" approach to vaccines is dated.
     
    "We may be able to reduce costs. We may be able to reduce the amount of side-effects. If you only need half as much vaccine to reach the same level of protection, we are adding cost, and potentially risk, by giving you double what you actually need."
    (Time stamp 3:30.)
     
    "If we have seen this kind of dramatic difference with this vaccine, will we see it with another vaccine? The answer is yes. We have seen that with other vaccines."
    (Time stamp 3:50.)
     
    Wow. EVERY legislator needs to see this video!! Stop the presses, this video needs everyone to see it!
     
    I'm still fascinated about the impaired CYP450 detoxification (of pharmaceuticals and adjuvants) occurring in some races and wondering if that isn't a variable of the "more responsive" immunity Poland is observing.
     
    The whole point of the adjuvants is to increase responsiveness to the vaccine, per my understanding. It would follow that 'too much' adjuvant creates hyper-immune responses (ie autoimmunity issues over time).
     
    We need a transcript of this video before it disappears.
     
    Mayo Clinic: http://newsnetwork.mayoclinic.org/discussion/mayo-clinic-discovers-african-americans-respond-better-to-rubella-vaccine/
  20. Like
    EAMom reacted to kim in Autism Occurrence by MMR Vaccine Status Among US Children With Older Siblings With and Without Autis   
    eamom,
     
    I started something on the Hep b thread and kind of dropped the ball. I think you might get a lot out of some of Hilary Butler's work on the immune system.
     
    http://www.beyondconformity.org.nz/hilarys-desk/vaccines-and-neonatal-immune-development
     
    about 1/3 of the way down, you'll see this
     
     
    What was so enlightening about this series was the fact that some of the vaccines were forcing a T cell dependent response when a baby is programmed not to have that response. Remember when I linked to the offit paper about how he acted like forcing that to happen was just the greatest thing? If you take polysaccharides and attach a protein and absorb it on aluminum, you get an anamnestic or memeory response (rise in titer after challenge/re exposure). When polysaccharides alone are used in infants or elderly, that doesn't work very well and you can actually get hyporesponsiveness. Think S pneumonia here and HiB.
     
    She also explains in "going viral," how the pertussis vaccine allows the mutation of the virus. I kept reading about the vaccinated being more susceptible and how the mutation was in response to the vaccine, but I didn't know how or why.
     
    http://www.beyondconformity.org.nz/hilarys-desk/going-viral-part-2
  21. Like
    EAMom reacted to searching_for_help in The media and vaccines, important for all   
    No matter what your take is on vaccines, I think this video is important for all. I am not "pro-vaccine", and not necessarily "anti-vaccine." My friends and family on Facebook seem to think you have to be either for or against. Personally, I have made some people very angry at the mere mention some vaccines MIGHT not be safe! I do believe some vaccines have saved lives, and others are dangerous. I also know that "anti-vaccers" are being blamed for breakouts that are really due to some of the vaccines not being affective, and the CDC knows this but doesn't correct the situation. This video brings up some of my concerns that are rarely discussed, and it's not so much the thimerosol (although that is important), but the way the vaccine manufacturers are making a fortune off these vaccines and our government has made it where they can't be sued. These companies get sued for billions of dollars for their shenanigans with their other drugs, why would we expect them to be honest about research with the vaccines, when they know they can't be sued?
     
    This video is of Bill Maher and Robert Kennedy, Jr. Kennedy points out the CDC can't be trusted, which I agree they have been bought off. Revolving door with lucrative paying jobs between the CDC and the vaccine manufacturers. He even mentioned Dr. Offit, his patents and the money he made off the deal. He also points out that REAL science is not always in agreement with the safety the CDC claims, but everyone blindly follows the CDC recommendations. (I don't think he pointed out that the pro-vaccine movement will immediately ruin anyone's reputation if they suggest ALL vaccines and the schedules aren't perfectly safe, but I see this all the time.)
     
    And my favorite is one of Bill Maher's comments. It has to do with what I consider my more "educated" friends, who on Facebook will literally call anyone who questions vaccines "idiots" and "dangerous". They completely trust the "industry", and although I think it's pretty clear Maher is for vaccines and doesn't know much about the discrepancy, he thinks it odd they put so much trust into for-profit companies that can buy off people. So do I.
     
    Here's the link, and I apologize if someone has already posted this one.
    http://www.boughtmovie.com/robert-f-kennedy-jr-real-time-with-bill-maher/
  22. Like
    EAMom reacted to kim in Vaccine Exemptions in CA   
    eamom,
     
    I am involved in my state at a local and state level. While working on all of this, the concerns AW refers to about the resurgence of measles has not been lost on me. I have a fear of varicella and measles particularly for autoimmune prone and OLDER age of onset. My kids got their first MMR at 12 mos. Again, parents are left in a horrible position here, for ourselves and our children. Thanks for posting
     
    I'm probably going to edit this down to just the links, but I found this information concerning.
     
    All bolding mine
     
    Volume 16, Issue 20, December 1998, Pages 2052–2057
    http://www.sciencedirect.com/science/article/pii/S0264410X98000814
    Abstract

    Vaccine-induced measles virus antibodies after two doses of combined measles, mumps and rubella vaccine: a 12-year follow-up in two cohorts

    In Finland, a two-dose vaccination programme against measles, mumps and rubella (MMR) was begun in 1982. The programme with high coverage (97–98%) has eliminated these three diseases from Finland. The aim of the present study was to follow up the kinetics of measles virus antibodies in MMR vaccinated cohorts. We have followed the kinetics of measles virus antibody levels induced by vaccination in the same individuals immunized with their first MMR vaccine in 1982. After 12 years 80% of the original children remained available for sampling. Antibodies to measles virus were measured by haemagglutination inhibition (HI) and plaque reduction neutralization (NT) techniques. The primary dose induced 99.4% seroconversion for measles with a geometric mean HI antibody titre (GMT) of (±219), equivalent to 4304 mIU (milli-International Units) ml-1 in group A. The 12-year follow-up specimens showed a measles seropositivity rate of 100% as assayed with the HI and NT tests with a mean HI antibody titre of (±54), equivalent to 624 mIU ml-1. The vaccination-induced measles virus antibodies decline in the absence of natural booster infections. It is important to follow how long the protection achieved by the present vaccine programme will last after elimination of indigenous measles.

    http://pediatrics.aappublications.org/content/132/5/e1126.full

    Measles in Children Vaccinated With 2 Doses of MMR

    OBJECTIVE: A previous measles outbreak investigation in a high school in Quebec, Canada identified 2-dose vaccine effectiveness of 94%. The risk of measles in 2-dose recipients was significantly higher (2–4 times) when measles vaccine was first administered at 12 versus =15 months of age, with no significant effect of the age at second dose. Generalizability of this association was also assessed in the expanded provincial data set of notified cases.

    METHODS: This matched case–control study included only 2-dose recipients. All confirmed (laboratory or epidemiologically linked) cases in patients aged 5 to 17 years were included. Each case was matched to 5 controls.

    RESULTS: A total of 102 cases and 510 controls were included; 89% of cases were in patients 13 to 17 years old. When the first dose was administered at 12 to 13 months compared with =15 months of age, the risk of measles in participants outside the outbreak school was 6 times higher (95% confidence interval, 1.33–29.3) and was 5.2 times higher (95% confidence interval, 1.91–14.3) in the pooled estimate (participants from the outbreak school + outside that school).

    CONCLUSIONS: A significantly greater risk of measles among 2-dose recipients whose first dose was given at 12 to 13 months rather than =15 months of age is confirmed in the larger Quebec data set. The mechanism remains unknown, but vaccine failures in 2-dose recipients could have substantial implications for measles elimination efforts through 2-dose vaccination. The optimal age at first dose may warrant additional evaluation.

    3rd paragraph under discussion
    A pooled fivefold greater risk of measles among those whose first MMR dose was administered at 12 to 13 vs =15 months is concerning, especially in the context of measles elimination efforts that require high levels of immunity. Previous serologic studies7,10,22–26 based on age at first dose are consistent with our epidemiologic observations. Although caution is needed in the interpretation of immunogenicity findings based on laboratory, assay, and protective thresholds applied, serologic studies have shown that early age at first dose leaves an imprint that affects both the immediate second-dose antibody response and persistence. Children first vaccinated at 12 months compared with =13 months are less likely to seroconvert after reimmunization and to have significantly lower antibody levels.10 This phenomenon has also been noted in children vaccinated younger than 12 months.7,22,23 Children without detectable plaque reduction neutralization antibody after a first dose responded to revaccination with a primary-type response and maintained antibody titers after revaccination above levels believed to be protective, whereas revaccination of children with low levels of plaque reduction neutralization antibody induced a secondary-type response, with antibodies returning rapidly to levels below protective threshold.24 In Germany, among ~7000 2-dose recipients, the proportion without detectable antibodies decreased steadily with older age at first dose to reach a nadir between 18 and 23 months.25 The proportion seronegative also increased with time since the second dose, and the proportion seronegative =6 years after the second dose was similar to that observed in single-dose recipients.25 Similarly, in the United States, increased antibody titers in response to a second MMR dose rapidly returned to prebooster levels, and most subjects (72%, 13/18) with low titers 10 years after boosting were also in the lowest quartile for antibodies before boost.26 This “return” to the level of protection afforded by the first dose based on time elapsed since the second dose is consistent with the similar VE we observed after 1 or 2 doses (95.9% vs 94.2%, respectively) during our recent school outbreak investigation.15

    and

    Conclusions

    Although unvaccinated people should remain the prime target for measles vaccination, the unexpected vulnerability we have identified in twice-vaccinated people could ultimately lead to failed measles elimination efforts. If the effect of early vaccination permanently alters the ability to respond to subsequent doses, even adding a third or fourth dose may not provide long-lasting protection. Therefore, it is critical to understand the mechanisms of primary vaccine failure or loss of vaccine protection that our findings may signal.

    http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=40001&fileId=S0950268899003222
    Epidemiology and Infection
    Epidemiology and Infection / Volume 124 / Issue 02 / April 2000, pp 263-271

    Abstract

    Failure to seroconvert (primary vaccine failure) is believed to be the principal reason (approx. > 95%) why some vaccinees remain susceptible to measles and is often attributed to the persistence of maternal antibodies in children vaccinated at a young age. Avidity testing is able to separate primary from secondary vaccine failures (waning and/or incomplete immunity), but has not been utilized in measles epidemiology. Low-avidity (LA) and high-avidity (HA) virus-specific IgG antibodies indicate primary and secondary failure, respectively. Measles vaccine failures (n = 142; mean age 10·1 years, range 2–22 years) from an outbreak in 1988–9 in Finland were tested for measles–virus IgG avidity using a protein denaturating EIA. Severity of measles was recorded in 89 failures and 169 non-vaccinees (mean age 16·2 years, range 2–22 years). The patients with HA antibodies (n = 28) tended to have clinically mild measles and rapid IgG response. Among failures vaccinated at < 12, 12–15 and > 15 months of age with single doses of Schwarz-strain vaccine in the 1970s, 50 (95% CI 1–99), 36 (CI 16–56) and 25% (CI 8–42) had HA antibodies, respectively. When a single measles, mumps and rubella (MMR) vaccine had been given after 1982 at 15 months of age, only 7% (CI 0–14) showed HA antibodies. Omitting re-vaccinees and those vaccinated at < 15 months, Schwarz-strain recipients had 3·6 (CI 1·1–11·5) higher occurrence of HA responses compared to MMR recipients. Apart from one municipality, where even re-vaccinees had high risk of primary infection, 89% (CI 69 to [similar] 100) of the infected re-vaccinees had an HA response. Secondary measles-vaccine failures are more common than was more previously thought, particularly among individuals vaccinated in early life, long ago, and among re-vaccinees. Waning immunity – even among individuals vaccinated after 15 months of age, without the boosting effect of natural infections should be considered a relevant possibility in future planning of vaccination against measles.
  23. Like
    EAMom reacted to sf_mom in Vaccine Exemptions in CA   
    Here's why you cannot be passive about SB277. If SB277 passes, it will take effect this January, and these will be the consequences:
     
    Your child will be forced to be vaccinated and re-vaccinated with 10 vaccines, including Hepatitis B, even though that is not communicable in a school setting. And your child will be re-vaccinated for diseases s/he may still be immune to from his/her last vaccinations. Any other of the almost 300 vaccines in development can be added to that schedule at any time. Do you want your child getting a fast-tracked Ebola vaccine? An anti-obesity vaccine? If you think you might want to opt out of even one of the coming vaccines, this Bill will prevent you from doing that. If you delay even one vaccine for your child, you will be forced to homeschool If you skip one vaccine, you will be forced to homeschool If you seek a medical exemption from vaccines so your child can continue to attend public or private school, your current pediatrician is highly unlikely to do it. You will have to:Track down a doctor willing to write an exemption (there are very few) Pay for an appointment out of network ($300-500) Pay for laboratory testing to bolster your exemption Have your new doctor write and sign medical exemptions and put it on her/his letterhead Hope that the doctor you find will grant your child(ren) medical exemptions from ALL the vaccines you think they shouldn't have right now, or those you want to split up or delay Hope that the doctor you find will grant your child(ren) permanent exemptions from vaccines, not just temporary File the medical exemptions with the school and your current pediatrician And, after SB277, we are certain the state will start to crack down on medical exemptions and try to define what qualifies as a medical exemption. They may or may not allow those with current medical exemptions to be "grandfathered." After that, they will come after the adults and make laws forcing adults to have vaccines, too. Right now, there is concurrent legislation in California for health care workers and for daycare workers to have mandatory vaccines.
  24. Like
    EAMom reacted to kim in Vaccine Exemptions in CA   
    nicklemama
     
    you need to be mad, not scared (believe me..i do know what you meant by that tho). When you discuss that Tdap with your Dr. print what the CDC/FDA are saying and take it!
     
    all bolding and underlining mine
    http://www.cdc.gov/maso/facm/pdfs/BSCOID/2013121112_BSCOID_Minutes.pdf

    Meeting of the Board of Scientific Counselors, Office of Infectious Diseases
    Centers for Disease Control and Prevention
    Tom Harkins Global Communication Center
    Atlanta, Georgia
    December 11
    -12, 2013

    Page 6

    Resurgence of Pertussis.
     
    As reported at the May 2013 BSC meeting, the recent resurgence in
    pertussis cases has been associated with waning immunity over time in persons who received the
    acellular pertussis vaccine (which is administered as the pertussis component of DTaP vaccine).
    However, a recent study suggests another explanation for decreased vaccine effectiveness: an
    increase in Bordetella pertussis isolates that lack pertactin (PRN)--
    a key antigen component of the acellular pertussis vaccine. A study that screened
    B. pertussis strains isolated between 1935 and 2012
    for gene insertions that prevent production of PRN found significant increases in PRN-
    deficient isolates throughout the United States.2
    The earliest PRN-deficient strain was isolated in 1994; by
    2012, the percentage of PRN-deficient isolates was more than 50%.


    To assess the clinical significance of these findings, CDC used an
    IgG anti-PRN ELISA and otherassays (PCR amplification, sequencing, and Western blots)
    to characterize 752 B. pertussis strains isolated in 2012 from six
    Enhanced Pertussis Surveillance Sites 3 and from epidemics in Washington
    and Vermont. Findings indicated that 85% of the isolates were PRN
    -deficient and vaccinated patients had significantly higher odds
    than unvaccinated patients of being infected with PRN-deficient strains.
    Moreover, when patients with up-to-date DTaP
    vaccinations were compared to unvaccinated patients,the odds of being infected with PRN-
    deficient strains increased, suggesting that PRN-bacteria may
    have a selective advantage in infecting DTaP-vaccinated persons.
     
    Ask him why he is insisting on giving your child the SIXTH aluminum adjuvanted vaccine when he (she) now knows
    that it will not result in protecting an infant because the short term boost your son may get is not going to prevent
    colonization/infection and transmisssion to a vulnerable infant/immunocompromised, but may mask symptoms that will encourage transmission.
    Not only that, ask him if he's ever read Cherry's paper about "original antigentic sin," or how it is thought that the original imprint
    on the immune system makes it harder to fight the mutated strain.
     
    Going back to the underlined Vermont outbreak underlinedlined above...here is what a couple of people reported
    http://vtdigger.org/2012/12/17/mullin-whooping-cough-numbers-show-vaccine-rates-need-to-be-higher/
    excerpts
     
    and
     
    http://vtdigger.org/2012/10/08/90-percent-of-whooping-cough-cases-in-vermont-among-vaccinated-children/
     
    excerpt
     
     
     
    To see Pan stammer about vaccinating for pertussis in the video posted in response above, it seems CRIMINAL that a periatrician is not warning parents of what's going on here and using it to perpetuate the situation by forcing the vaccine to attend daycare and pubic school.
     
    If i were a Dr. being forced into this situation and an infant in my practice died or a child in the community, I just can't imagine sleeping at night.
    They need to speak up!
  25. Like
    EAMom reacted to nicklemama in Rheumatic disorders developed after hepatitis B vaccination   
    I wish I'd been smarter about vaccines when DS was a baby.
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