My son is 15 years old and weighs 120lb. I give him 43mg in the morning and 43mg in the evening. So daily he is getting a total of 86mg. I would start with a lower dose and continue to increase until you see results. My sons tics increase when he takes a lower dose. The dose he is on now I consider therapeutic. I started with 20mg in the morning and 20mg in the evening. I would take into concideration weight and age of the person getting the hemp oil. Some people see results with as little as 10mg just depends on the person. If you would like a little more info about how hemp oil helps tourettes look up One Life Radio. I just did an interview with them on June 13th. They talk about the endocannabinoid system. I hope this help.