Report Tics and (cortico)steroids? in Tourette Syndrome and Tics Posted August 26, 2010 · Edited August 26, 2010 by guy123 most steroids are dopaminergic dopamine increases tics in people with TS Right I understand that, but I'm asking why in one case (PANDAS) it reduces tics and in the other case (TS) it exacerbates them. edit - I didn't see your second reply before I posted my reply. Nevermind. When your husband had his steroid burst (prednisone?) did his tics ever return to baseline? If so, how long did it take?