Report Mycoplasma again... in PANS / PANDAS (Lyme included) Posted January 23, 2018 My son takes 250 mg a day and 500 a day when he has a regression. He has taken it for over 2 years now. My oldest daughter takes 250 mg a day and my youngest takes 4 liquid ML's a day. Without the Zithromax they are all a mess. With it, they do great. It is hard to process that they are taking long term strong antibiotics. But without it they don't have a good life.