Tourettes Medication that doesn't have sedation effect in Tourette Syndrome and Tics Posted October 18, 2018 · Report reply 1 hour ago, jason_dfw said: Here is what is working pretty well in managing my 14 year old son's (5'9 and 180lbs so adult size) tics. 1mg guanfacine tablet in AM and 1mg in PM before bed. With his size he is authorized to take up to 4mg per day, however the tics are controlled enough with 2mg that we want to avoid potential drowsiness and weight gain that can be a side effect. 100mg B6 tablet in AM 200mg magnesium citrate tablet in AM and 200mg in PM before bed. We used Natural Calm for a while with good success, however my son hates the taste of the powder and the Natural Calm gummies became non-existent due to some kind of manufacturing issue by Natural Calm. The tablets seem to be doing the trick, so will not return to Natural Calm. We tried other magnesium types, however citrate appears to be the correct type of mag, as the other types had limited to no impact. We try to avoid artificial colors and flavors when possible, but otherwise he pretty much eats what he wishes. He is very active in sports and tics big time when playing sports, but that's when the dopamine is really flowing, so it's expected. Otherwise, the tics are very slight with this routine. Thanks for your response. Would you mind sharing the brand of B6 and magensium citrate with me? Thanks.