Report RASH - did/does you child have one? in PANS / PANDAS (Lyme included) Posted May 16, 2016 My DS15 has had a rash that comes and goes. It always shows up during IVIG but it is kind of like a hot flash.and in that it only stays for 1-10 minutes and then goes away. It is not raised - just red and has presented two ways. It is on his chest, shoulders and neck. It is is large red splotches or it is a weird non uniform outline (kind like the grout in a walk way flagstone. The rash also shows up occasionally in between monthly IVIGs. It showed up yesterday and it is 28 days post his last IVIG. My son's immunologist and neurologist do not have an answer for the rash. My son has had some great success with IVIG and steroids but nothing is holding. I feel like this rash has to be a clue but I don't know for what so I thought I would ask if anyone else's child has experienced this rash and know what is means? Thanks for your help. Also - he has been tested by IGenix for Lyme and co-infections and was negative.