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Elizabeth

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  1. A helpful guide for us in dealing with autoimmunity and PANS was; "identify the triggers" , "address infection (strep, gut dysbiosis, mycoplasma)" "heal the barrier systems (gut, blood brain barrier)" and "reduce inflammation". In regards to tumeric/ curcumin, here is a Pub Med research article from March 2014, and one from the Journal of Neuroinflammation". http://www.ncbi.nlm.nih.gov/pubmed/24382451 Exp Neurol. 2014 Mar;253:102-10. doi: 10.1016/j.expneurol.2013.12.016. Epub 2013 Dec 29. Curcumin protects axons from degeneration in the setting of local neuroinflammation. http://www.jneuroinflammation.com/content/8/1/125 Conclusions Collectively, our results suggest that curcumin is a potent modulator of the microglial transcriptome. Curcumin attenuates microglial migration and triggers a phenotype with anti-inflammatory and neuroprotective properties. Thus, curcumin could be a nutraceutical compound to develop immuno-modulatory and neuroprotective therapies for the treatment of various neurodegenerative disorders.
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