[B-12 shots]

We have been doing them now for approximately 6 weeks. My son was diagnosed with PANDAS right before his 4th birthday, he is now 6 years old and recently diagnosed with a mutation on the MTHFR gene. He receives methylcobalamin vitamin b12 shots every other day. We have definitely noticed improvement in his symptoms....causes some hyper activity but our doctor says that should subside.

[Severe reaction to 4th HD IVIG-thoughts?]

I am no expert by any means however I am a nurse and my son has PANDAS and is currently receiving IVIG. The best advice I could give you is to start hydrating 2 days prior to treatment and 2 days post treatment. Medicate with Benadryl and Tylenol through out course of infusion and monitor the rate. I wonder if the rate had been increased on that 4th treatment .....rate has a lot to do with side effects. Try bumping down the rate with the next infusion to see if that helps. Good Luck