Report LDN - Low Dose Naltroxone. Has anyone tried it? in PANS / PANDAS (Lyme included) Posted August 28, 2015 Has anyone tried this to regulate the immune system? Does it work? Side effects? Recommended for my dd 7, but not a cream a pill at night. Im intrigued but just looking to see what others have seen? Also, I know its not an acute cure but more of a long term thing, right?