Hello. Our son, age 6, has been doing so well on zithromycin. We recently changed doctors because we were driving almost 4 hours for a while until we found out a local pediatrician is DAN certified and has a lot of experience with PANDAS. We continued the zithromycin for a while and now he has recommended the Bicillin monthly injectable. Our son has had his first dose and is due for his second one next week. We saw some regression the first few days which has me so worried but they said it was not unusual to see some regression before things got better again. Now it has been about 3 weeks and he is doing better but has at least a few OCD "moments" a day still. I know that is not a lot by any means but when I compare it to how there were absolutely NO signs of OCD in him at all, not even one little bit for all those weeks/months when he was on the zithromycin, I am not sure what to think. I am happy that he is still doing so much better than he was when we initially sought treatment for PANDAS but I don't know why the zithromycin seemed to work better. By the way, his titers have dropped from 700 to 500 since last year, but have remained at 500 for the last several months whenever he has been tested. I guess the zithromycin did not lower the titers much although it drastically improved symptoms. I am wondering if the Bicillin will lower the titers significantly but the trade off is, it doesn't work as well. I wish I knew the reason why some meds work better for some kids and others work better for other kids...anyone have any idea?
Thanks! Maria