Report Grapefruit seed extract is doing something in PANS / PANDAS (Lyme included) Posted December 3, 2013 Dd8, following in the footsteps of dd11 has become incredibly rageful. Like dd11, he has lyme/Bart/babesia. He had very high titers for ebv (igg). Until now, he has been hyper with clothing sensitivities, OCD, and periodic inability to handle any frustration. He has responded to some things that I don't often see mentioned. Like, for a while, lysine knocked out his extreme anger, but then that stopped working. 5 days ago we started grapefruit seed extract, and it has calmed him, no question about it. He can still be hyper and uncontrollably silly, but it completely took the anger away and brought back sweet. Last night it started to wear off toward the end of a long day, and he fell asleep without the gse. This morning he woke up with anger x10. Advil calmed him some, but he was just downright mean--calling me a dummy, a jerk, yelling at me in the meanest voice--he did not hit me, but I could feel it coming--he has never done that before, but he was furious--over basically my presence. I know that gse can be helpful with yeast and probably breaking up biofilms....but specifically, with the biofilms I'd expect a herx instead of rapid improvement. Is there another reason it could be helping? Also, he was so out of control today that I called one of the PANDAS immunologists that we have seen, and they had just had a cancellation and can take him tomorrow. I'm starting to pack. Here's hoping the second kiddo will have an easier fix.