Is it true that Sammy had ONE sudden onset episode, with nothing minor brewing previously, and from that ONE sudden onset, he went chronic? I mean, that was it, right? He contracted asymptomatic strep at age 10, mom had no idea, and he went from bad to worse and stayed there until high dose abx, correct? No sawtooth whatsoever? Is that pretty unusual, even among all us zebras? Or at least unusual for the over 5 y.o. child?
I'm TOTALLY speculating, but I wonder if Sammy was more the "got the really nasty strain of strep" kind of PANDAS and that those kind of PANDAS are the ones with the chronically high DNAse B; totally my wild speculation. Are these the "hyper-immune" kiddos and theoretically, there bodies are chronically co-producing an abundance of DNAse B, ASO (?) and anti-neuronal antibodies? That's why they can be "tracked" by DNAseB titers? So, they managed to achieve an "immuno-cool down" with high dose abx over several years... Is this the same or similar nasty strain in Dawn's family with the crazy high titers? (How r u all doing, btw?)
Another note, and take this for what it is worth, but when Dr. T spoke publicly with Beth several months back, he commented that Sammy continued to exhibit mild signs of OCD. The mother later requested he retract that statement, which he did. Dr T. said he made that comment based on his observations of the young man not on parent or patient's report. So, he saw something, albeit probably mild and not interfering with Sammy being a successful, accomplishing young man (maybe he was shaking his foot, rubbing his eyebrow, clearing his throat or shifting in his chair in a chronic, repetitive manner that would only be noticed if you were looking for it?) It is with this in mind that I wonder if Sammy did indeed have any minor signs brewing as a child that were just "invisible" to the mom's eyes?
Last thing, promise; Is the ONE abx case being referred to by those discussing Dr. K's position; is that WorriedDad's child who did not experience success with multiple ivig, but has had success on high dose Augmentin or is that ONE an early detection case?
Edited by JAG10, 20 July 2010 - 09:10 AM.